Preprint / Version 1

Exploring of Antimicrobial Activity of Triphala Mashi—an Ayurvedic Formulation

Authors

  • Yogesh Biradar Department of Pharmacognosy, Poona College of Pharmacy, Bharati Vidyapeeth Deemed University, Erandwane, Pune 411 038, 2Department of Microbiology, University of Pune and 3Department of Management Sciences, University of Pune, Pune, Maharashtra, India
  • Sheetal Jagatap Department of Pharmacognosy, Poona College of Pharmacy, Bharati Vidyapeeth Deemed University, Erandwane, Pune 411 038, 2Department of Microbiology, University of Pune and 3Department of Management Sciences, University of Pune, Pune, Maharashtra, India
  • K Khandelwal Department of Pharmacognosy, Poona College of Pharmacy, Bharati Vidyapeeth Deemed University, Erandwane, Pune 411 038, 2Department of Microbiology, University of Pune and 3Department of Management Sciences, University of Pune, Pune, Maharashtra, India
  • Smita Singhania Department of Pharmacognosy, Poona College of Pharmacy, Bharati Vidyapeeth Deemed University, Erandwane, Pune 411 038, 2Department of Microbiology, University of Pune and 3Department of Management Sciences, University of Pune, Pune, Maharashtra, India

Keywords:

antimicrobial activity, clinical sample and Tannin, Triphala, Triphala Mashi

Abstract

Triphala Mashi is an ayurvedic formulation that was prepared in our lab. Aqueous and alcoholic extracts of both Triphala and Triphala Mashi were used, to evaluate antimicrobial activity. Comparative phytochemical profile of Triphala and Triphala Mashi was done by preliminary phytochemical screening, total phenolic content and thin layer chromatography (TLC). Antimicrobial activity includes isolation of pathogens from clinical samples, its characterization, testing its multiple drug resistance against standard antibiotics and antimicrobial activity of aqueous and alcoholic extracts of both Triphala and Triphala Mashi against these organisms by using agar gel diffusion method. Triphala Mashi containing phenolic compounds, tannins exhibited comparable antimicrobial activity in relation to Triphala against all the microorganisms tested. It inhibits the dose-dependent growth of Gram-positive and Gram-negative bacteria. In conclusion, it appears that Triphala Mashi has non-specific antimicrobial activity. Keywords: antimicrobial activity, clinical sample and Tannin, Triphala, Triphala Mashi

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