A comparative pharmacological evaluation of Taila (oil) and Ghrita (ghee) prepared with Guduchi (Tinospora cordifolia)
Authors
Ranjita Vaghamshi
Medical Officer, Govt. Ayurveda Hospital, Kolki, Ta.-Upaleta, Dist.-Rajkot, India
Mundeep Jaiswal
Lecturer, Department of Rasa Shastra & Bhaishajya Kalpana, State Ayurvedic College & Hospital, Lucknow, Uttar Pradesh, India
B Patgiri
Associate Professor, Department of RS & BK including Drug Research, Institute for Post Graduate Teaching and Research in Ayurveda, Jamnagar, India
P Prajapati
Professor and Head, Department of RS & BK including Drug Research, Institute for Post Graduate Teaching and Research in Ayurveda, Jamnagar, India
B Ravishankar
Ex. Head, Pharmacology Laboratory, Institute for Post Graduate Teaching and Research in Ayurveda, Jamnagar, India
V Shukla
Head, Pharmaceutical Chemistry Laboratory, Institute for Post Graduate Teaching and Research in Ayurveda, Jamnagar, Gujarat, India
Guduchi (Tinospora cordifolia wild miers) is a well-known medicinal plant, which is abundantly used in different ayurvedic formulations utilizing varieties of media. The drug has properties like Rasayana (rejuvenating property), Krimighna (anthelmintics), and Kushtghna (used in skin disorders), as described in ayurvedic literature. Taila (oil) and Ghrita (ghee) are used as media in Ayurvedic Sneha (oleaginous) formulations. Both the test drugs, Guduchi Taila and Ghrita, are prescribed in Vatrakta (gout) and also indicated for Kushtha (skin disorder). With all these details, the Guduchi Taila and Guduchi Ghrita samples, prepared by using Taila and Ghrita as media, have been subjected to comparative pharmacological investigations, to assess the impact of the media on the expression of pharmacological activity. The formulations have been evaluated for immunomodulation, anti-inflammatory, and anti-stress activities. Both the formulations have been found to be active in most of the experiments, however, with the change of media, their results vary at different levels. Taila prepared from Guduchi was found to have an immunostimulating activity. The formulation prepared with Ghrita exhibited an anti-stress effect with an immunosuppressing activity.
Keywords: Guduchi (Tinospora cordifolia wild miers), Guduchi Taila, Guduchi Ghrita, Immunomodulation, Anti-inflammatory, Anti-stress
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