Standardization of Shadbindu Taila: An Ayurvedic oil based medicine
Authors
Sunita Shailajan
Associate Professor, Department of Botany and In-charge, Herbal Research Laboratory, Ramnarain Ruia College, Matunga, Mumbai, Maharashtra, India
Sasikumar Menon
Assistant Director, Institute for Advanced Training and Research in Interdisciplinary Sciences (Therapeutic Drug Monitoring Laboratory), Sion Koliwada, Mumbai, Maharashtra, India
Bhavesh Tiwari
Research Scholar, Herbal Research Laboratory, Ramnarain Ruia College, Matunga, Mumbai, Maharashtra, India
Ashish Singh
Research Scholar, Institute for Advanced Training and Research in Interdisciplinary Sciences (Therapeutic Drug Monitoring Laboratory), Sion Koliwada, Mumbai, Maharashtra, India
Keywords:
High performance thin layer chromatography, kaempferol, safety, Shadbindu Taila, standardization
Abstract
Shadbindu Taila (ST) is an Ayurvedic formulation used as a remedy for loosening of tooth, weakness of the eyesight, loss of hair, diseases of head, etc., Present study is an attempt to develop some newer approaches for the quality control and standardization of ST. Standardized operating procedure for the preparation of ST was developed in accordance with Ayurvedic Formulary of India. Preliminary phytochemical, physicochemical, and chromatographic evaluation of ST was carried out. Safety of ST was evaluated in terms of skin irritation test and presence of heavy metals. Chemical characterization of ST was done on the basis of kaempferol using validated -High Performance Thin Layer Chromatographic (HPTLC) method. ST did not show presence of any of the heavy metals analyzed and was found non-irritant on rabbit skin. The quality control parameters resulted after scientific evaluation of ST can be used as reference standard for quality control/assurance laboratory of a pharmaceutical firm in order to have a proper quality check over its preparation and processing.
Keywords: High performance thin layer chromatography, kaempferol, safety, Shadbindu Taila, standardization
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