Preprint / Version 1

Antiurolithiatic Activity of Gokhsuradi Churan, an Ayurvedic Formulation By In Vitro Method

Authors

  • Ashok Srinivasa Department of Pharmacognosy, Sri K.V.College of Pharmacy, Chickballapur, Karnataka, India.
  • Lakshman Kuruba Department of Pharmacognosy, PES College of Pharmacy, Bangalore, Karnataka, India.
  • Saleemulla Khan Department of Pharmacognosy, Manipal College of Pharmceutical Sciences, Manipal, Karnataka, India.
  • Gopi Saran Department of Pharmacognosy, Sri K.V.College of Pharmacy, Chickballapur, Karnataka, India.

Keywords:

Gokhsuradi churna, Antiurolethiatic activity, Calcium oxalate, Nucleation

Abstract

Purpose: Gokhsuradi churna is an ayurvedic formulation, was investigate for antiurolithiatic activity. Methods: Calcium oxalate crystallization was induced by the addition of 0.01M sodium oxalate solutions in synthetic urine and nucleation method. Results: The effect of Gokhsuradi Churna exhibited a concentration dependent inhibition of on calcium oxalate crystallization and nucleation. Conclusion: The present studies suggest that Gokhsuradi churna has a potential inhibition of calcium oxalate crystallization exhibited and nucleation. Gokhsuradi Churna showed potent antiurolethiatic activity. Keywords: Gokhsuradi churna, Antiurolethiatic activity, Calcium oxalate, Nucleation

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