Protective effect of Lannea coromandelica Houtt. Merrill. against three common pathogens
Authors
Rupinder Kaur
Department of Dravyaguna, National Institute of Ayurveda, Jaipur, India
Mohan Jaiswal
Department of Dravyaguna, National Institute of Ayurveda, Jaipur, India
Vivek Jain
Department of Pharmacy, Faculty of Science and Technology, Banasthali Vidhyapith, Tonk, Rajasthan, India
Keywords:
Agar well diffusion method, antibacterial, antifungal, ayurveda, Candida albicans, female reproductive tract infection, Lannea coromandelica, Staphylococcus aureus, Streptococcus pyogens
Abstract
Ayurvedic text reports suggested Lannea coromandelica is used in various microbial origin disorders like dysentery, sore eyes and leprosy, genital wounds.
Objective:
The present study was designed to investigate the antimicrobial effect of L. coromandelica Houtt. Merrill. (Anacardiaceae) on microbes which cause female reproductive tract infection.
Materials and Methods:
Ethanolic and aqueous bark extract (Ext.) of L. coromandelica were screened against strains of Streptococcus pyogens, Staphylococcus aureus, and Candida albicans. Antimicrobial assay had been done with agar well diffusion method.
Results:
Ethanolic extracts [100% (16 mg), 75% (12 mg) and 50% (8 mg)] of L. coromandelica exhibited zone of inhibition (ZI) 19.21 mm, 18.45 mm, 16.41 mm and 18.12 mm, 17.35 mm, 16.35 mm against S. aureus and S. pyogens, respectively. However, only 100% and 75% ethanolic extract showed (ZI-19.18 mm, 16.29 mm) activity against C. albicans. Nevertheless, aqueous extract (100%) showed higher antifungal activity (ZI-16.97 mm). Ciprofloxacin and amphotericin B were used as a standard drugs in the present study.
Conclusion:
The results demonstrated that L. coromandelica Houtt. Merrill. have antibacterial activity against S. pyogens, S. aureus and antifungal property against C. albicans. Our findings corroborate the ethnobotanical use of L. coromandelica in traditional medicine system (Ayurveda) of India.
Keywords: Agar well diffusion method, antibacterial, antifungal, ayurveda, Candida albicans, female reproductive tract infection, Lannea coromandelica, Staphylococcus aureus, Streptococcus pyogens
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