Preprint / Version 1

Turmeric - A new treatment option for lichen planus: A pilot study

Authors

  • Vibha Singh Department of Oral and Maxillofacial Surgery, KGMU, Lucknow, Uttar Pradesh, India
  • Mahesh Pal Department of Oral and Maxillofacial Pathology, NBRI, Lucknow, Uttar Pradesh, India
  • Shalini Gupta Department of Oral and Maxillofacial Pathology, KGMU, Lucknow, Uttar Pradesh, India
  • S Tiwari Department of Oral and Maxillofacial Pathology, NBRI, Lucknow, Uttar Pradesh, India
  • Laxman Malkunje Department of Oral and Maxillofacial Surgery, KGMU, Lucknow, Uttar Pradesh, India
  • Somdipto Das Department of Oral and Maxillofacial Surgery, KGMU, Lucknow, Uttar Pradesh, India

Keywords:

Antioxidants, lichenplanus, turmeric

Abstract

Turmeric is dried rhizome of the perennial herbs curcumalonga. It is called Haldi in Hindi, turmeric in English, ukon in Japanese. It has been used in Asian Medicine since the second millennium BC. It's utility is referred to in the ancient Hindu script the Ayurveda. Pathogenesis of the OLP should be taken in consideration for the treatment point of view. The Cell mediated immunity to secondary antigenic change in oral mucous membrane is thought to play a major role in its pathogenesis modified keratocyte surface antigens are the primary target for cytotoxic cellular response. Curcumin also been shown to have immune modulatory effect involving activation of host macrophages and natural killer cells and modulation of lymphocytes mediated function. Keywords: Antioxidants, lichenplanus, turmeric