Insights from Ayurveda for translational stem cell research
Authors
Kalpana Joshi
Department of Biotechnology, Sinhgad College of Engineering, University of Pune, Maharashtra, India
Ramesh Bhonde
Department of Biotechnology, Manipal School of Regenerative Medicine, Bangalore, Karnataka, India
Keywords:
Ayurveda, rasayana, stem cells
Abstract
Ayurveda, the traditional Indian system of medicine has given great emphasis to the promotion of health. Ayurveda therapies are based on restoration of body balance and nourishment of dhatus or tissues. Rasayana concept of Ayurveda explains tissue regeneration and cell renewal. The drugs and therapies explained as rasayana provide research opportunities for biology of regeneration. Specific rasayana stimulate and nourish respective dhatus. Interpretation of this description offers clues for specific differentiation of stem cells with appropriate extract. The preliminary experiments on Medhya drugs suggest neuronal stem cells differentiation. Authors highlight the potential of Ayurveda and its possible contributions in regenerative medicine. Authors propose a protocol based on integrative approach derived from Ayurveda concepts and current understanding of regenerative medicine. The advanced understanding about adult and embryonic stem cells along with concepts of regeneration in Ayurveda has immense potential in the development of regenerative medicine.
Keywords: Ayurveda, rasayana, stem cells
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