The prevalence of dyslipidemia in patients with diabetes mellitus of ayurveda Hospital
Authors
Amit Dixit
Department of Pathology and Biochemistry, National Research Institute of Ayurvedic Drug Development, Department of AYUSH, Government of India, 4 CN Block, Sec-5, Bidhannagar, Kolkata 700091, West Bengal, India
Ranjit Dey
Department of Pathology and Biochemistry, National Research Institute of Ayurvedic Drug Development, Department of AYUSH, Government of India, 4 CN Block, Sec-5, Bidhannagar, Kolkata 700091, West Bengal, India
Aela Suresh
Department of Pathology and Biochemistry, National Research Institute of Ayurvedic Drug Development, Department of AYUSH, Government of India, 4 CN Block, Sec-5, Bidhannagar, Kolkata 700091, West Bengal, India
Siddhartha Chaudhuri
Department of Pathology and Biochemistry, National Research Institute of Ayurvedic Drug Development, Department of AYUSH, Government of India, 4 CN Block, Sec-5, Bidhannagar, Kolkata 700091, West Bengal, India
Ashok Panda
Hospital Division, National Research Institute of Ayurvedic Drug Development, Department of AYUSH, Government of India, 4 CN Block, Sec-5, Bidhannagar, Kolkata 700091, West Bengal, India
Achintya Mitra
Hospital Division, National Research Institute of Ayurvedic Drug Development, Department of AYUSH, Government of India, 4 CN Block, Sec-5, Bidhannagar, Kolkata 700091, West Bengal, India
Jayram Hazra
Hospital Division, National Research Institute of Ayurvedic Drug Development, Department of AYUSH, Government of India, 4 CN Block, Sec-5, Bidhannagar, Kolkata 700091, West Bengal, India
Dyslipidemia is one of the major risk factors for cardiovascular disease in diabetes mellitus. Early detection and treatment of dyslipidemia in type-2 diabetes mellitus can prevent risk for atherogenic cardiovascular disorder. The rationale of this study was to detect the lipid abnormality in diabetic patients.
Methods
Necessary data was collected from the medical archives of 150 patients (73 female and 77 male) with diabetes mellitus registered in Department of pathology and biochemistry of a Ayurveda hospital established at Kolkata, India.
Results
The mean ages of female and male subjects were 51.8 ± 10.8 and 53.2 ± 11.3 years respectively. The range and mean value of FBS in females were 113–342 mg/dl and 157.7 ± 6.3 mg/dl, while the range and mean value of PPBS in females were 135–560 mg/dl and 275.5 ± 12.3 mg/dl respectively. Results showed that range and mean value of FBS in males were 111–462 mg/dl and 160.8 ± 7.4 mg/dl, while the range and mean value of PPBS in males were 136–598 mg/dl and 302.1 ± 12.6 mg/dl respectively. Results of serum lipids showed that the mean values for total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and very low density lipoprotein cholesterol (VLDL-C) in female patients were 202.2 ± 5.9 mg/dl, 168.3 ± 8.2 mg/dl, 44.9 ± 1.3 mg/dl, 123.6 ± 5.2 mg/dl and 33.7 ± 1.7 mg/dl respectively. The mean values for TC, TG, HDL-C, LDL-C and VLDL-C in male patients were 182.5 ± 4.8 mg/dl, 128.1 ± 10.8 mg/dl, 40.8 ± 1.2 mg/dl, 105.4 ± 4.8 mg/dl and 36.2 ± 2.2 respectively. FBS showed significant positive correlation with PPBS, cholesterol, TG, and VLDL-C. PPBS also demonstrated direct and significant correlations with TG and VLDL-C.
Conclusions
The study showed common lipid abnormalities during diabetes induced dyslipidemia i.e., hypercholesterolemia, hypertriglyceridemia and elevated LDL-C. This study suggests the dominance of hyperlipidemia over increased prevalence of dyslipidemia.
Keywords: Diabetes mellitus, Blood sugar, Dyslipidemia, Hyperlipidemia, Lipid profile
Click on "Archives" to access the full archive of scientific preprints. You may use the categories and the search functionality to find select preprints you're interested in.
