Preprint / Version 1

Medicinal Plants and Cancer Chemoprevention

Authors

  • Avni Desai Department of Environmental Health Sciences [A.G.D., H.K.B.], Mailman School of Public Health, Columbia University, New York, NY; Department of Surgery [M.E-T], College of Physicians and Surgeons, Columbia University, New York, NY; Department of Pathology, Ohio State University, Columbus, Ohio [RKG]; Indian Institute of Integrative Medicine [J.S., A.K.S., Y.S.B., S.C.T., G.N.Q.], Council of Scientific and Industrial Research Jammu-Tawi, India
  • Ghulam Qazi Department of Environmental Health Sciences [A.G.D., H.K.B.], Mailman School of Public Health, Columbia University, New York, NY; Department of Surgery [M.E-T], College of Physicians and Surgeons, Columbia University, New York, NY; Department of Pathology, Ohio State University, Columbus, Ohio [RKG]; Indian Institute of Integrative Medicine [J.S., A.K.S., Y.S.B., S.C.T., G.N.Q.], Council of Scientific and Industrial Research Jammu-Tawi, India
  • Ramesh Ganju Department of Environmental Health Sciences [A.G.D., H.K.B.], Mailman School of Public Health, Columbia University, New York, NY; Department of Surgery [M.E-T], College of Physicians and Surgeons, Columbia University, New York, NY; Department of Pathology, Ohio State University, Columbus, Ohio [RKG]; Indian Institute of Integrative Medicine [J.S., A.K.S., Y.S.B., S.C.T., G.N.Q.], Council of Scientific and Industrial Research Jammu-Tawi, India
  • Mahmoud El-Tamer Department of Environmental Health Sciences [A.G.D., H.K.B.], Mailman School of Public Health, Columbia University, New York, NY; Department of Surgery [M.E-T], College of Physicians and Surgeons, Columbia University, New York, NY; Department of Pathology, Ohio State University, Columbus, Ohio [RKG]; Indian Institute of Integrative Medicine [J.S., A.K.S., Y.S.B., S.C.T., G.N.Q.], Council of Scientific and Industrial Research Jammu-Tawi, India
  • Jaswant Singh Department of Environmental Health Sciences [A.G.D., H.K.B.], Mailman School of Public Health, Columbia University, New York, NY; Department of Surgery [M.E-T], College of Physicians and Surgeons, Columbia University, New York, NY; Department of Pathology, Ohio State University, Columbus, Ohio [RKG]; Indian Institute of Integrative Medicine [J.S., A.K.S., Y.S.B., S.C.T., G.N.Q.], Council of Scientific and Industrial Research Jammu-Tawi, India
  • Ajit Saxena Department of Environmental Health Sciences [A.G.D., H.K.B.], Mailman School of Public Health, Columbia University, New York, NY; Department of Surgery [M.E-T], College of Physicians and Surgeons, Columbia University, New York, NY; Department of Pathology, Ohio State University, Columbus, Ohio [RKG]; Indian Institute of Integrative Medicine [J.S., A.K.S., Y.S.B., S.C.T., G.N.Q.], Council of Scientific and Industrial Research Jammu-Tawi, India
  • Yashbir Bedi Department of Environmental Health Sciences [A.G.D., H.K.B.], Mailman School of Public Health, Columbia University, New York, NY; Department of Surgery [M.E-T], College of Physicians and Surgeons, Columbia University, New York, NY; Department of Pathology, Ohio State University, Columbus, Ohio [RKG]; Indian Institute of Integrative Medicine [J.S., A.K.S., Y.S.B., S.C.T., G.N.Q.], Council of Scientific and Industrial Research Jammu-Tawi, India
  • Subhash Taneja Department of Environmental Health Sciences [A.G.D., H.K.B.], Mailman School of Public Health, Columbia University, New York, NY; Department of Surgery [M.E-T], College of Physicians and Surgeons, Columbia University, New York, NY; Department of Pathology, Ohio State University, Columbus, Ohio [RKG]; Indian Institute of Integrative Medicine [J.S., A.K.S., Y.S.B., S.C.T., G.N.Q.], Council of Scientific and Industrial Research Jammu-Tawi, India
  • Hari Bhat Department of Environmental Health Sciences [A.G.D., H.K.B.], Mailman School of Public Health, Columbia University, New York, NY; Department of Surgery [M.E-T], College of Physicians and Surgeons, Columbia University, New York, NY; Department of Pathology, Ohio State University, Columbus, Ohio [RKG]; Indian Institute of Integrative Medicine [J.S., A.K.S., Y.S.B., S.C.T., G.N.Q.], Council of Scientific and Industrial Research Jammu-Tawi, India

Keywords:

Medicinal plants, natural products, ayurveda, cancer, alternative medicine

Abstract

Cancer is the second leading cause of death worldwide. Although great advancements have been made in the treatment and control of cancer progression, significant deficiencies and room for improvement remain. A number of undesired side effects sometimes occur during chemotherapy. Natural therapies, such as the use of plant-derived products in cancer treatment, may reduce adverse side effects. Currently, a few plant products are being used to treat cancer. However, a myriad of many plant products exist that have shown very promising anti-cancer properties in vitro, but have yet to be evaluated in humans. Further study is required to determine the efficacy of these plant products in treating cancers in humans. This review will focus on the various plant-derived chemical compounds that have, in recent years, shown promise as anticancer agents and will outline their potential mechanism of action. Keywords: Medicinal plants, natural products, ayurveda, cancer, alternative medicine

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