Preprint / Version 1

Antidiabetic potential of some less commonly used plants in traditional medicinal systems of India and Nigeria

Authors

  • Abubakar Mohammed Department of Biochemistry, University of Allahabad, Allahabad, Uttar Pradesh, India
  • Dileep Kumar Department of Biochemistry, University of Allahabad, Allahabad, Uttar Pradesh, India
  • Syed Rizvi Department of Biochemistry, University of Allahabad, Allahabad, Uttar Pradesh, India

Keywords:

Antidiabetic plants, diabetes, hypoglycaemic activity, medicinal plants, oxidative stress

Abstract

The incidence of diabetes mellitus continue to rise annually all over the world with India and Nigeria having recorded cases of 65.1 and 3.9 million respectively in 2013 and expected to increase by a large amount in 2035. Hyperglycemia is a pre-condition for the development of diabetic complications and is accompanied by an increase in the production of free radicals. The present available treatment option for diabetes like sulfonylurea, metformin and alpha-glucosidase are restricted by their limited actions, secondary failure rates, and side-effects; and unaffordable to the majority of the population. Hence, the need to screen for more medicinal plants with antidiabetic ability due to the fact that plants are; biodegradable, safe and cheap with fewer side-effects. In this review article, we have presented the current status of diabetes in India and Nigeria and the role of some less commonly used medicinal plants from both countries that have antidiabetic potential. Keywords: Antidiabetic plants, diabetes, hypoglycaemic activity, medicinal plants, oxidative stress

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