Syzygium cumini (L.) skeels: a prominent source of bioactive molecules against cardiometabolic diseases
Authors
Vinicyus Chagas
Laboratory of Experimental Physiology, Department of Physiological Sciences, Federal University of Maranhão, São Luís, Brazil
Lucas França
Laboratory of Experimental Physiology, Department of Physiological Sciences, Federal University of Maranhão, São Luís, Brazil
Sonia Malik
Graduate Program in Health Sciences, Biological and Health Sciences Center, Federal University of Maranhão, São Luís, Brazil
Antonio Paes
Laboratory of Experimental Physiology, Department of Physiological Sciences, Federal University of Maranhão, São Luís, Brazil
Keywords:
black plum, jamun, myrtaceae, phenolic compounds, metabolic syndrome, ethnopharmacology, medicinal plants, complementary and alternative medicine
Abstract
Syzygium cumini (Myrtaceae) is a worldwide medicinal plant traditionally used in herbal medicines due to its vaunted properties against cardiometabolic disorders, which include: antihyperglycemic, hypolipemiant, antiinflammatory, cardioprotective, and antioxidant activities. These properties have been attributed to the presence of bioactive compounds such as phenols, flavonoids, and tannins in different parts of the plant, albeit the knowledge on their mechanisms of action is scarce. This mini-review highlights the cardiometabolic properties of S. cumini by correlating its already identified phytochemicals with their described mechanisms of action. Data herein compiled show that some compounds target multiple metabolic pathways; thereby, becoming potential pharmacological tools. Moreover, the lack of clinical trials on S. cumini usage makes it a fruitful field of interest for both scientific community and pharmaceutical industry.
Keywords: black plum, jamun, myrtaceae, phenolic compounds, metabolic syndrome, ethnopharmacology, medicinal plants, complementary and alternative medicine
Author Biographies
Vinicyus Chagas, Laboratory of Experimental Physiology, Department of Physiological Sciences, Federal University of Maranhão, São Luís, Brazil
Graduate Program in Health Sciences, Biological and Health Sciences Center, Federal University of Maranhão, São Luís, Brazil
Lucas França, Laboratory of Experimental Physiology, Department of Physiological Sciences, Federal University of Maranhão, São Luís, Brazil
Graduate Program in Health Sciences, Biological and Health Sciences Center, Federal University of Maranhão, São Luís, Brazil
Antonio Paes, Laboratory of Experimental Physiology, Department of Physiological Sciences, Federal University of Maranhão, São Luís, Brazil
Graduate Program in Health Sciences, Biological and Health Sciences Center, Federal University of Maranhão, São Luís, Brazil
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