Preprint / Version 1

Pharmaceutical standardization of Kamsaharitaki granules

Authors

  • Nidhi Khemuka Department of Rasashastra and Bhaishajya Kalpana, Govt. Ayurved College, Jabalpur, Madhya Pradesh, India
  • R Galib Department of Rasashastra and Bhaishajya Kalpana Including Drug Research, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India
  • Biswa Patgiri Department of Rasashastra and Bhaishajya Kalpana Including Drug Research, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India
  • Pradeep Prajapati Department of Rasashastra and Bhaishajya Kalpana Including Drug Research, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India

Keywords:

Granules, Kamsaharitaki Avaleha, Khanda Paka, standardization

Abstract

Introduction: Kamsaharitaki Avaleha is a well-known ayurvedic preparation. Considering certain inconveniences of Avaleha, an attempt has been made to convert it into granules that are convenient in handling, dispensing, and storage. Aim: To convert Kamsaharitaki Avaleha into granules form and develop standard manufacturing procedure. Materials and Methods: Seven pilot batches were prepared to fix the ratio of formulation composition. The procedure was repeated for 14 times to ensure the process validation. Results: Converting into granules in presence of jaggery and Haritaki pulp is found to be difficult. Replacing these two with Khanda Sharkara and Haritaki powder yielded desired characteristics of granules. Conclusion: This modified proportion of ingredients can be considered as standard in preparing Kamsaharitaki Avaleha granules. As no manufacturing and physicochemical properties are available for Kamsaharitaki granules; the current findings can be considered as standard for future studies. Keywords: Granules, Kamsaharitaki Avaleha, Khanda Paka, standardization

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