Dorin Dragos
Medical Semiology Department, Faculty of General Medicine, “Carol Davila” University of Medicine and Pharmacy, B-dul “Eroilor Sanitari” nr. 8, Sector 6, 76241 Bucharest, Romania; [email protected]
Marilena Gilca
Biochemistry Department, Faculty of General Medicine, “Carol Davila” University of Medicine and Pharmacy, B-dul “Eroilor Sanitari” nr. 8, Sector 6, 76241 Bucharest, Romania; [email protected] (M.G.); [email protected] (L.G.)
Laura Gaman
Biochemistry Department, Faculty of General Medicine, “Carol Davila” University of Medicine and Pharmacy, B-dul “Eroilor Sanitari” nr. 8, Sector 6, 76241 Bucharest, Romania; [email protected] (M.G.); [email protected] (L.G.)
Adelina Vlad
Physiology Department, Faculty of General Medicine, “Carol Davila” University of Medicine and Pharmacy, B-dul “Eroilor Sanitari” nr. 8, Sector 6, 76241 Bucharest, Romania; [email protected]
Liviu Iosif
R&D IRIST LABMED SRL, Str. Miraslau, nr. 24, Sector 3, 031235 Bucharest, Romania; [email protected]
Irina Stoian
Biochemistry Department, Faculty of General Medicine, “Carol Davila” University of Medicine and Pharmacy, B-dul “Eroilor Sanitari” nr. 8, Sector 6, 76241 Bucharest, Romania; [email protected] (M.G.); [email protected] (L.G.)
Olivera Lupescu
Orthopaedic and Trauma Clinic 2, Faculty of General Medicine, “Carol Davila” University of Medicine and Pharmacy, 020022 Bucharest, Romania; [email protected]
Chronic joint inflammatory disorders such as osteoarthritis and rheumatoid arthritis have in common an upsurge of inflammation, and oxidative stress, resulting in progressive histological alterations and disabling symptoms. Currently used conventional medication (ranging from pain-killers to biological agents) is potent, but frequently associated with serious, even life-threatening side effects. Used for millennia in traditional herbalism, medicinal plants are a promising alternative, with lower rate of adverse events and efficiency frequently comparable with that of conventional drugs. Nevertheless, their mechanism of action is in many cases elusive and/or uncertain. Even though many of them have been proven effective in studies done in vitro or on animal models, there is a scarcity of human clinical evidence. The purpose of this review is to summarize the available scientific information on the following joint-friendly medicinal plants, which have been tested in human studies: Arnica montana, Boswellia spp., Curcuma spp., Equisetum arvense, Harpagophytum procumbens, Salix spp., Sesamum indicum, Symphytum officinalis, Zingiber officinalis, Panax notoginseng, and Whitania somnifera.
Keywords: osteoarthritis, rheumatoid arthritis, medicinal plants, herbs
Author Biographies
Dorin Dragos, Medical Semiology Department, Faculty of General Medicine, “Carol Davila” University of Medicine and Pharmacy, B-dul “Eroilor Sanitari” nr. 8, Sector 6, 76241 Bucharest, Romania; [email protected]
Nephrology Clinic, University Emergency Hospital Bucharest, 050098 Bucharest, Romania
Irina Stoian, Biochemistry Department, Faculty of General Medicine, “Carol Davila” University of Medicine and Pharmacy, B-dul “Eroilor Sanitari” nr. 8, Sector 6, 76241 Bucharest, Romania; [email protected] (M.G.); [email protected] (L.G.)
R&D IRIST LABMED SRL, Str. Miraslau, nr. 24, Sector 3, 031235 Bucharest, Romania; [email protected]
Olivera Lupescu, Orthopaedic and Trauma Clinic 2, Faculty of General Medicine, “Carol Davila” University of Medicine and Pharmacy, 020022 Bucharest, Romania; [email protected]
Clinical Emergency Hospital Bucharest, 014461 Bucharest, Romania
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