Health Effects of Psidium guajava L. Leaves: An Overview of the Last Decade
Authors
Elixabet Díaz-de-Cerio
Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Avd. Fuentenueva s/n, 18071 Granada, Spain; [email protected] (E.D.-d.-C.); [email protected] (A.F.-G.); [email protected] (A.S.-C.)
Vito Verardo
Department of Nutrition and Food Science, University of Granada, Campus of Cartuja, 18071 Granada, Spain; [email protected]
Ana Gómez-Caravaca
Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Avd. Fuentenueva s/n, 18071 Granada, Spain; [email protected] (E.D.-d.-C.); [email protected] (A.F.-G.); [email protected] (A.S.-C.)
Alberto Fernández-Gutiérrez
Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Avd. Fuentenueva s/n, 18071 Granada, Spain; [email protected] (E.D.-d.-C.); [email protected] (A.F.-G.); [email protected] (A.S.-C.)
Antonio Segura-Carretero
Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Avd. Fuentenueva s/n, 18071 Granada, Spain; [email protected] (E.D.-d.-C.); [email protected] (A.F.-G.); [email protected] (A.S.-C.)
Keywords:
Psidium guajava L. (guava) leaves, traditional medicine, in vitro, in vivo, phenolic compounds, pharmacology
Abstract
Today, there is increasing interest in discovering new bioactive compounds derived from ethnomedicine. Preparations of guava (Psidium guajava L.) leaves have traditionally been used to manage several diseases. The pharmacological research in vitro as well as in vivo has been widely used to demonstrate the potential of the extracts from the leaves for the co-treatment of different ailments with high prevalence worldwide, upholding the traditional medicine in cases such as diabetes mellitus, cardiovascular diseases, cancer, and parasitic infections. Moreover, the biological activity has been attributed to the bioactive composition of the leaves, to some specific phytochemical subclasses, or even to individual compounds. Phenolic compounds in guava leaves have been credited with regulating blood-glucose levels. Thus, the aim of the present review was to compile results from in vitro and in vivo studies carried out with guava leaves over the last decade, relating the effects to their clinical applications in order to focus further research for finding individual bioactive compounds. Some food applications (guava tea and supplementary feed for aquaculture) and some clinical, in vitro, and in vivo outcomes are also included.
Keywords: Psidium guajava L. (guava) leaves, traditional medicine, in vitro, in vivo, phenolic compounds, pharmacology
Author Biographies
Elixabet Díaz-de-Cerio, Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Avd. Fuentenueva s/n, 18071 Granada, Spain; [email protected] (E.D.-d.-C.); [email protected] (A.F.-G.); [email protected] (A.S.-C.)
Functional Food Research and Development Center, Health Science Technological Park, Avd. Del Conocimiento, Bioregion Building, 18100 Granada, Spain
Alberto Fernández-Gutiérrez, Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Avd. Fuentenueva s/n, 18071 Granada, Spain; [email protected] (E.D.-d.-C.); [email protected] (A.F.-G.); [email protected] (A.S.-C.)
Functional Food Research and Development Center, Health Science Technological Park, Avd. Del Conocimiento, Bioregion Building, 18100 Granada, Spain
Antonio Segura-Carretero, Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Avd. Fuentenueva s/n, 18071 Granada, Spain; [email protected] (E.D.-d.-C.); [email protected] (A.F.-G.); [email protected] (A.S.-C.)
Functional Food Research and Development Center, Health Science Technological Park, Avd. Del Conocimiento, Bioregion Building, 18100 Granada, Spain
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