Preprint / Version 1

Clinical evaluation of Vatari guggulu, Maharasnadi kwatha and Narayan taila in the management of osteoarthritis knee

Authors

  • Anil Mangal aNational Research Institute for Ayurveda Siddha Human Resource Development (NRIASHRD), Central Council for Research in Ayurvedic Sciences, Gwalior, Madhya Pradesh, India
  • MN Shubhasree bNational Ayurveda Dietetics Research Institute (NADRI), Central Council for Research in Ayurvedic Sciences, Bangalore, Karnataka, India
  • Pramila Devi cAchanta Lakshmipati Research Centre for Ayurveda (ALCRA), Central Council for Research in Ayurvedic Sciences, Chennai, India
  • AD Jadhav aNational Research Institute for Ayurveda Siddha Human Resource Development (NRIASHRD), Central Council for Research in Ayurvedic Sciences, Gwalior, Madhya Pradesh, India
  • Sai Prasad bNational Ayurveda Dietetics Research Institute (NADRI), Central Council for Research in Ayurvedic Sciences, Bangalore, Karnataka, India
  • Kisore Kumar cAchanta Lakshmipati Research Centre for Ayurveda (ALCRA), Central Council for Research in Ayurvedic Sciences, Chennai, India
  • Sarada Otta dCentral Council for Research in Ayurvedic Sciences (CCRAS), New Delhi, India
  • KS Dhiman dCentral Council for Research in Ayurvedic Sciences (CCRAS), New Delhi, India

Keywords:

Ayurvedic medicine, Osteoarthritis, Sandhivata, Vatari guggulu, Maharasnadi kwatha, Narayana taila

Abstract

In present era, pharmacological, bio-chemical and surgical interventions are not success remedy for Osteoarthritis (OA). Ayurveda and other complementary medicine have medication for OA. Objectives The main aim of the study was to assess the efficacy and safety of therapeutic combination of Vatari guggulu along with Maharasnadi kwatha and Narayan taila with gentle massage for 15 min daily up to 12 weeks on affected knee joint pain assessed on Visual analogue scale (VAS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Materials and methods It was an open label, multicentre, prospective, clinical study conducted on 142 patients of OA Knee. Vatari guggulu 500 mg thrice in a day along with Maharasnadi kwatha 20 ml with equal amount of water twice daily and Narayan taila 20 ml twice in a day for external application with gentle massage for 15 min up to 12 weeks were used to all the study participants. Results VAS, WOMAC score and clinical symptoms were reduced significantly from baseline to end of the treatment (P < 0.001). Conclusions The study provides good evidence in support of the efficacy and safety of the Vatari guggulu along with Maharasnadi kwatha and Narayan taila in the management of Osteoarthritis knee. Keywords: Ayurvedic medicine, Osteoarthritis, Sandhivata, Vatari guggulu, Maharasnadi kwatha, Narayana taila

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