Medicinal Profile, Phytochemistry, and Pharmacological Activities of Murraya koenigii and Its Primary Bioactive Compounds
Authors
Rengasamy Balakrishnan
Department of Applied Life Sciences and Integrated Bioscience, Graduate School, Konkuk University, Chungju 27478, Korea; [email protected] (R.B.); [email protected] (S.-H.J.)
Dhanraj Vijayraja
Department of Biochemistry, Rev. Jacob Memorial Christian College, Ambilikkai 624612, Tamilnadu, India; [email protected]
Song-Hee Jo
Department of Applied Life Sciences and Integrated Bioscience, Graduate School, Konkuk University, Chungju 27478, Korea; [email protected] (R.B.); [email protected] (S.-H.J.)
Palanivel Ganesan
Department of Integrated Bio Science and Biotechnology, College of Biomedical and Health Science, Nanotechnology Research Center, Konkuk University, Chungju 27478, Korea; [email protected]
In Su-Kim
Department of Applied Life Sciences and Integrated Bioscience, Graduate School, Konkuk University, Chungju 27478, Korea; [email protected] (R.B.); [email protected] (S.-H.J.)
Dong-Kug Choi
Department of Applied Life Sciences and Integrated Bioscience, Graduate School, Konkuk University, Chungju 27478, Korea; [email protected] (R.B.); [email protected] (S.-H.J.)
Keywords:
Murraya koenigii, antioxidant, bioactive compounds, pharmacological activity, traditional medicine
Abstract
The discovery of several revitalizing molecules that can stop or reduce the pathology of a wide range of diseases will be considered a major breakthrough of the present time. Available synthetic compounds may provoke side effects and health issues, which heightens the need for molecules from plants and other natural resources under discovery as potential methods of replacing synthetic compounds. In traditional medicinal therapies, several plant extracts and phytochemicals have been reported to impart remedial effects as better alternatives. Murraya koenigii (M. koenigii) belongs to the Rutaceae family, which is commonly used as a medicinally important herb of Indian origin in the Ayurvedic system of medicine. Previous reports have demonstrated that the leaves, roots, and bark of this plant are rich sources of carbazole alkaloids, which produce potent biological activities and pharmacological effects. These include antioxidant, antidiabetic, anti-inflammatory, antitumor, and neuroprotective activities. The present review provides insight into the major components of M. koenigii and their pharmacological activities against different pathological conditions. The review also emphasizes the need for more research on the molecular basis of such activity in various cellular and animal models to validate the efficacy of M. koenigii and its derivatives as potent therapeutic agents.
Keywords: Murraya koenigii, antioxidant, bioactive compounds, pharmacological activity, traditional medicine
Author Biography
Dong-Kug Choi, Department of Applied Life Sciences and Integrated Bioscience, Graduate School, Konkuk University, Chungju 27478, Korea; [email protected] (R.B.); [email protected] (S.-H.J.)
Department of Integrated Bio Science and Biotechnology, College of Biomedical and Health Science, Nanotechnology Research Center, Konkuk University, Chungju 27478, Korea; [email protected]
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