Characterization of biotite drugs used in traditional medicine
Authors
Apsara Wijenayake
aPostgraduate Institute of Science, University of Peradeniya, Peradeniya, Sri Lanka
Amarasooriya Pitawala
aPostgraduate Institute of Science, University of Peradeniya, Peradeniya, Sri Lanka
Ratnayake Bandara
aPostgraduate Institute of Science, University of Peradeniya, Peradeniya, Sri Lanka
Charmalie Abayasekara
aPostgraduate Institute of Science, University of Peradeniya, Peradeniya, Sri Lanka
Keywords:
Earth sciences, Geochemistry, Health sciences, Nano particles, Thermal oxidation, Detoxification, Biotite mica, Traditional medicine
Abstract
Temperature-induced mineral alterations are extensively used in traditional pharmaceutical industry. Studies on the traditional heating methods for enhancing pharmaceutical properties and on the toxicity of mineral-based medicines are limited. This study focuses on the effect of thermal alterations on mineralogical and chemical changes of biotite with respect to two traditional drugs (Abhrak Bhasma and Abhrak Chendhuram). Samples of the drugs and heat-treated and untreated biotite minerals were characterized using X-ray diffraction analysis, Fourier-transform infra-red spectroscopy, thermogravimetric analysis and differential scanning calorimetry. Total and water-soluble cation concentrations of drugs were measured using atomic absorption spectrometry. The study reveals that the degree of collapsing the biotite structure increased with the thermal oxidation process that produced nanoparticles of crystalline and amorphous iron oxides and secondary silicates. The thermal products of biotite had nano-crystallinity and high water solubility. The study suggests that modern pharmaceuticals can be developed from mineral-based traditional drugs.
Keywords: Earth sciences, Geochemistry, Health sciences, Nano particles, Thermal oxidation, Detoxification, Biotite mica, Traditional medicine
Author Biographies
Apsara Wijenayake, aPostgraduate Institute of Science, University of Peradeniya, Peradeniya, Sri Lanka
bDepartment of Geology, Faculty of Science, University of Peradeniya, Peradeniya, Sri Lanka
Amarasooriya Pitawala, aPostgraduate Institute of Science, University of Peradeniya, Peradeniya, Sri Lanka
bDepartment of Geology, Faculty of Science, University of Peradeniya, Peradeniya, Sri Lanka
Ratnayake Bandara, aPostgraduate Institute of Science, University of Peradeniya, Peradeniya, Sri Lanka
cDepartment of Chemistry, Faculty of Science, University of Peradeniya, Peradeniya, Sri Lanka
Charmalie Abayasekara, aPostgraduate Institute of Science, University of Peradeniya, Peradeniya, Sri Lanka
dDepartment of Botany, Faculty of Science, University of Peradeniya, Peradeniya, Sri Lanka
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