GermiX: A skin friendly hand sanitizer with prolonged effectivity against pathogenic bacteria
Authors
Acharya Balkrishna
Drug Discovery and Development Division, Patanjali Research Institute (Governed By Patanjali Research Foundation Trust), Roorkee-Haridwar Road, Haridwar, Uttarakhand 249405 India
Kanchan Singh
Drug Discovery and Development Division, Patanjali Research Institute (Governed By Patanjali Research Foundation Trust), Roorkee-Haridwar Road, Haridwar, Uttarakhand 249405 India
Hoshiyar Singh
Drug Discovery and Development Division, Patanjali Research Institute (Governed By Patanjali Research Foundation Trust), Roorkee-Haridwar Road, Haridwar, Uttarakhand 249405 India
Swati Haldar
Drug Discovery and Development Division, Patanjali Research Institute (Governed By Patanjali Research Foundation Trust), Roorkee-Haridwar Road, Haridwar, Uttarakhand 249405 India
Anurag Varshney
Drug Discovery and Development Division, Patanjali Research Institute (Governed By Patanjali Research Foundation Trust), Roorkee-Haridwar Road, Haridwar, Uttarakhand 249405 India
Keywords:
Patanjali hand sanitizer, Prolonged surface retentivity, Hand sanitizer, Cost-effective
Abstract
COVID-19 pandemic has almost made hand sanitization a ritual resulting in a steep increase in the frequency of hand sanitization and an unprecedented surge in demand for hand sanitizers. In fact, several governments had to ration hand sanitizers in the retail outlets and over the counter chemist shops. Additionally, Indian government has put a cap on the prices of hand sanitizers. Currently, large sections of global and Indian population are grappling under financial crises. Therefore, mandatory hand sanitization has made an unwelcoming, yet unavoidable addition to the already-hard-to-maintain-grocery-list. Here, we have compared the anti-microbial efficacy of Patanjali Hand Sanitizer (PHS), developed and marketed by Patanjali Ayurved Ltd. (an India-based food and herbal medicine company) with one of the topmost hand sanitizers currently used under clinical set-ups. PHS has anti-microbial efficacy comparable to that of the standard hand sanitizer. Besides, disc diffusion and time-dependent thumb print assays showed that PHS has longer retentivity on the applied surfaces, suggesting lesser consumption of the sanitizer and concomitant relaxation on the monthly grocery budget. Observed anti-bacterial potency of PHS is attributed to the disruption of bacterial cell membrane, as employed by alcohol-based hand sanitizers. A rough estimation revealed that PHS is ~ 4.3 times cost effective than the standard hand sanitizer used as the positive control in this study. Taken together, PHS is a suitable alternative for existing hand sanitizers available in the market that can relax the demand–supply strain and soften significantly the burden of monthly expenditure on hand sanitizers.
Keywords: Patanjali hand sanitizer, Prolonged surface retentivity, Hand sanitizer, Cost-effective
Author Biographies
Acharya Balkrishna, Drug Discovery and Development Division, Patanjali Research Institute (Governed By Patanjali Research Foundation Trust), Roorkee-Haridwar Road, Haridwar, Uttarakhand 249405 India
Department of Allied and Applied Sciences, University of Patanjali, NH-58, Haridwar, Uttarakhand 249405 India
Anurag Varshney, Drug Discovery and Development Division, Patanjali Research Institute (Governed By Patanjali Research Foundation Trust), Roorkee-Haridwar Road, Haridwar, Uttarakhand 249405 India
Department of Allied and Applied Sciences, University of Patanjali, NH-58, Haridwar, Uttarakhand 249405 India
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