Cosmetic and Dermatological Properties of Selected Ayurvedic Plant Extracts
Authors
Martyna Zagórska-Dziok
Department of Technology of Cosmetic and Pharmaceutical Products, Medical College, University of Information Technology and Management in Rzeszow, Kielnarowa 386a, 36-020 Tyczyn, Poland; [email protected] (A.Z.); [email protected] (T.B.); [email protected] (Z.N.-Ł.)
Aleksandra Ziemlewska
Department of Technology of Cosmetic and Pharmaceutical Products, Medical College, University of Information Technology and Management in Rzeszow, Kielnarowa 386a, 36-020 Tyczyn, Poland; [email protected] (A.Z.); [email protected] (T.B.); [email protected] (Z.N.-Ł.)
Tomasz Bujak
Department of Technology of Cosmetic and Pharmaceutical Products, Medical College, University of Information Technology and Management in Rzeszow, Kielnarowa 386a, 36-020 Tyczyn, Poland; [email protected] (A.Z.); [email protected] (T.B.); [email protected] (Z.N.-Ł.)
Zofia Nizioł-Łukaszewska
Department of Technology of Cosmetic and Pharmaceutical Products, Medical College, University of Information Technology and Management in Rzeszow, Kielnarowa 386a, 36-020 Tyczyn, Poland; [email protected] (A.Z.); [email protected] (T.B.); [email protected] (Z.N.-Ł.)
Zofia Hordyjewicz-Baran
ŁUKASIEWICZ Research Network—Institute of Heavy Organic Synthesis “Blachownia”, Energetykow 9, 47-225 Kedzierzyn-Kozle, Poland; [email protected]
Due to the constantly growing interest in ingredients of natural origin, this study attempts to evaluate the possibility of using extracts from three Ayurvedic plants in preparations for the care and treatment of skin diseases. Therefore, studies of antioxidant properties were carried out using DPPH and ABTS radicals, obtaining 76% and 88% of these radical scavenging, respectively. A significant decrease in the intracellular level of free radicals and an increase in the activity of the antioxidant enzyme-superoxide dismutase by almost 60% were also observed. In addition, the extracts were assessed for anti-inflammatory and anti-aging properties, obtaining over 70% inhibition of lipoxygenase activity and almost 40% of collagenase. Additionally, the cytoprotective properties of the obtained extracts on skin cells, keratinocytes and fibroblasts, were demonstrated. To assess the content of biologically active compounds, HPLC-electrospray ionization (ESI)-MS/MS multiple reaction monitoring (MRM) analyses were performed. The obtained results show that all three analyzed plants are a valuable source of biologically active substances with desired properties in the context of skin cell protection. Particularly noteworthy is the extract of Epilobium angustifolium L., for which the most promising results were obtained.
Keywords: antioxidants, anti-inflammatory properties, lipoxygenase, anti-aging properties, collagenase, fibroblasts, keratinocytes, skin hydration
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