Preprint / Version 1

A comparative study of biological potentiality and EAC cell growth inhibition activity of Phyllanthus acidus (L.) fruit pulp and seed in Bangladesh

Authors

  • Ajmeri Shimu Molecular Biology and Protein Science Laboratory, Department of Genetic Engineering and Biotechnology, Faculty of Life and Earth Sciences, University of Rajshahi, Rajshahi 6205, Bangladesh
  • Masum Miah Molecular Biology and Protein Science Laboratory, Department of Genetic Engineering and Biotechnology, Faculty of Life and Earth Sciences, University of Rajshahi, Rajshahi 6205, Bangladesh
  • Mutasim Billah Molecular Biology and Protein Science Laboratory, Department of Genetic Engineering and Biotechnology, Faculty of Life and Earth Sciences, University of Rajshahi, Rajshahi 6205, Bangladesh
  • Sumon Karmakar Molecular Biology and Protein Science Laboratory, Department of Genetic Engineering and Biotechnology, Faculty of Life and Earth Sciences, University of Rajshahi, Rajshahi 6205, Bangladesh
  • Sumon Mohanto Molecular Biology and Protein Science Laboratory, Department of Genetic Engineering and Biotechnology, Faculty of Life and Earth Sciences, University of Rajshahi, Rajshahi 6205, Bangladesh
  • Ratna Khatun Molecular Biology and Protein Science Laboratory, Department of Genetic Engineering and Biotechnology, Faculty of Life and Earth Sciences, University of Rajshahi, Rajshahi 6205, Bangladesh
  • Md Reza Molecular Biology and Protein Science Laboratory, Department of Genetic Engineering and Biotechnology, Faculty of Life and Earth Sciences, University of Rajshahi, Rajshahi 6205, Bangladesh
  • Kazi Hoque Molecular Biology and Protein Science Laboratory, Department of Genetic Engineering and Biotechnology, Faculty of Life and Earth Sciences, University of Rajshahi, Rajshahi 6205, Bangladesh

Keywords:

Phyllanthus acidus, Antioxidant, Cytotoxicity, Phytochemicals, Lectin, EAC cell

Abstract

Highlights • The screening of biological activities of medicinal plants are emphasized due to the adverse effects of synthetic drugs. • The present study demonstrates antioxidant, cytotoxic, and haemagglutination activity as well as EAC cell growth inhibitory effect of methanolic extract of Phyllantus acidus (L.) (MEPA) fruit pulp and seed. • P. acidus is traditionally used as herbal medicine in China, Brazil, and South Asian countries like Bangladesh for the treatment of digestive, respiratory, genitourinary, and skin disorder. • The result of this study suggested that MEPA fruit pulp has a more antioxidant potentiality and EAC cell growth inhibitory property than seed which indicates the presence of effective phytochemicals in MEPA fruit pulp. • Therefore, the MEPA fruit pulp can be considered as a promising biological source to search novel compounds for therapeutic purposes. Keywords: Phyllanthus acidus, Antioxidant, Cytotoxicity, Phytochemicals, Lectin, EAC cell

Downloads