A randomized open label parallel group pilot study to evaluate efficacy of Ayurveda interventions in the management of asymptomatic and mild COVID-19 patients-experiences of a Lucknow based level 2 hospital of Uttar Pradesh, India
Authors
Adil Rais
aState Ayurvedic Hospital, Maharajganj, District Sultanpur, Uttar Pradesh, India
Devendra Negi
bMedical and Health Services, Lucknow, Uttar Pradesh, India
Amita Yadav
cLBRNCH, Lucknow, India
Himanshu Arya
dState Programme Management Unit, Mainstreaming of Ayush, NHM Uttar Pradesh, Lucknow, India
Ramji Verma
dState Programme Management Unit, Mainstreaming of Ayush, NHM Uttar Pradesh, Lucknow, India
R Galib
eDepartment of RSBK, All India Institute of Ayurveda, New Delhi, 110076, India
Absar Ahmad
fDepartment of Community Medicine, Manipal Tata Medical College, Manipal Academy of Higher Education, Jamshedpur, India
SARS--CoV-2 has emerged as a global threat since its onset in December 2019. India has also been severely affected by the dreadful Corona Virus and is currently battling one of the worst pandemics of history. WHO and the world medical fraternity are putting their efforts to materialize a treatment or vaccine for this novel virus. A randomized open label parallel group study was designed in a Lucknow based level 2 COVID hospital to evaluate the efficacy of Ayurvedic interventions in the management of asymptomatic and mild COVID 19 patients.
Objective
To evaluate the efficacy of Ayurveda in the management of mildly affected COVID-19 patients.
Materials and methods
The current trial was an open label randomized 10-day study. Total 120 asymptomatic and/or mild COVID-19 positive patients fulfilling inclusion criteria were randomly grouped into three. RT-PCR of all the patients were done on 5th, 7th and on 10th day respectively. The observations were noted and results were analyzed statistically. Kruskal–Wallis test and Wilcoxon Sign rank test were used for data analysis where applicable.
Results
Improvement in symptoms, enhancement in Agni and recovery from COVID infection was observed. The results obtained were encouraging and showed better viral clearance and control of symptom progression in the patients placed on Ayurvedic medications.
Conclusion
The promising results in the study showed that an approach involving Ayurveda can be helpful for the management of the mild COVID-19 patients. Ayurveda can be used to limit community spread and check disease progression to a more appalling state.
Trial registration
Trial was registered with Clinical Trials Registry- India (CTRI registration number: CTRI/2020/06/025800.
Keywords: Covid-19, Ayurveda, Randomized trial, Immunity, Agni
Click on "Archives" to access the full archive of scientific preprints. You may use the categories and the search functionality to find select preprints you're interested in.
