Preprint / Version 1

Scientific rationale of Indian AYUSH Ministry advisory for COVID-19 prevention, prophylaxis, and immunomodulation

Authors

  • Prashant Gupta Department of Balroga, Shri NPA Govt. Ayurveda College, Raipur (CG), India
  • Kishor Sonewane Department of Balroga, Shri NPA Govt. Ayurveda College, Raipur (CG), India
  • Mariappan Rajan Department of Natural Product Chemistry, Madurai Kamaraj University, Madurai, Tamil Nadu, India
  • Nitin Patil Department of Integrative Medicine, Sri Devraj Urs Academy of Higher Education and Research, Kolar, Karnataka India
  • Trapti Agrawal Department of Stri Roga & Prasuti Tantra, Chaudhary Brahm Prakash Ayurved Charak Sansthan, New Delhi, India
  • Ena Banerjee Department of Zoology, Immunology and Regenerative Medicine Research Unit, University of Calcutta, Kolkata, India
  • Nagendra Chauhan Drugs Testing Laboratory Avam Anusandhan Kendra (State Government Lab of AYUSH), Government Ayurvedic College, Raipur (CG), India
  • Awanish Kumar Department of Biotechnology, National Institute of Technology, Raipur (CG), 492010 India

Keywords:

COVID-19, Indian AYUSH advisory, Ayurveda, Immunomodulation, Therapy

Abstract

The current outbreak of COVID-19 is caused by the SARS-CoV-2 virus that has affected > 210 countries. Various steps are taken by different countries to tackle the current war-like health situation. In India, the Ministry of AYUSH released a self-care advisory for immunomodulation measures during the COVID-19 and this review article discusses the detailed scientific rationale associated with this advisory. Authors have spotted and presented in-depth insight of advisory in terms of immunomodulatory, antiviral, antibacterial, co-morbidity associated actions, and their probable mechanism of action. Immunomodulatory actions of advised herbs with no significant adverse drug reaction/toxicity strongly support the extension of advisory for COVID-19 prevention, prophylaxis, mitigations, and rehabilitation capacities. This advisory also emphasized Dhyana (meditation) and Yogasanas as a holistic approach in enhancing immunity, mental health, and quality of life. The present review may open-up new meadows for research and can provide better conceptual leads for future researches in immunomodulation, antiviral-development, psychoneuroimmunology, especially for COVID-19. Keywords: COVID-19, Indian AYUSH advisory, Ayurveda, Immunomodulation, Therapy

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