Preprint / Version 1

Mesenchymal stem cells as a platform for research on traditional medicine

Authors

  • Ramesh Bhonde aDr. D. Y. Patil Vidyapeeth, Pimpri, Pune, 411018, India
  • Avinash Sanap bRegenerative Medicine Laboratory, Dr. D. Y. Patil Dental College and Hospital, Pimpri, Pune, 411018, India
  • Kalpana Joshi dDepartment of Biotechnology, Sinhgad College of Engineering affiliated to Savitribai Phule Pune University, Pune, 411041, India

Keywords:

Evidence-based traditional medicines, Ayurveda, Mesenchymal stem cells

Abstract

The translation of Traditional Medicines (TMs) such as Ayurveda, and Traditional Chinese Medicine into clinical practice remains obstructed due to lack of scientific evidence by means of safety, quality, standardization, clinical efficacy, and mode of action. These limitations can be attributed to the lack of synonymous invitro models which reflect invivo features. Human mesenchymal stem cells (hMSCs) have emerged as an efficient cell source for regenerative medicine and tissue engineering. In this review, the authors discuss how hMSCs can be used as an invitro platform to screen herbs described in TMs using modern methods such as evaluation of its potential, safety, quality, mode of action, etc. Integration of traditional knowledge systems like Ayurveda and hMSCs as a platform to screen and study TMs using modern tools will effectively increase the validity of TMs as evidence-based medicine. Keywords: Evidence-based traditional medicines, Ayurveda, Mesenchymal stem cells

Author Biography

Avinash Sanap, bRegenerative Medicine Laboratory, Dr. D. Y. Patil Dental College and Hospital, Pimpri, Pune, 411018, India

cInterdisciplinary School of Health Sciences, Savitribai Phule University of Pune, Pune, 411007, India

Downloads