Quality Related Safety Evaluation of a South African Traditional Formulation (PHELA®) as Novel Anti-Biofilm Candidate

Bhaskar Das; Amit Kar; Rudranil Bhowmik; Sanmoy Karmakar; Satyajit Tripathy; Motlalepula Matsabisa; Pulok Mukherjee

Preprint / Version 1

Quality Related Safety Evaluation of a South African Traditional Formulation (PHELA®) as Novel Anti-Biofilm Candidate

Authors

Bhaskar Das Department of Pharmaceutical Technology, School of Natural Product Studies, Jadavpur University, Kolkata 700032, India; [email protected] (B.D.); [email protected] (R.B.); [email protected] (S.K.); [email protected] (P.K.M.)
Amit Kar Institute of Bioresources and Sustainable Development, Department of Biotechnology, Government of India, Imphal 795001, India; [email protected]
Rudranil Bhowmik Department of Pharmaceutical Technology, School of Natural Product Studies, Jadavpur University, Kolkata 700032, India; [email protected] (B.D.); [email protected] (R.B.); [email protected] (S.K.); [email protected] (P.K.M.)
Sanmoy Karmakar Department of Pharmaceutical Technology, School of Natural Product Studies, Jadavpur University, Kolkata 700032, India; [email protected] (B.D.); [email protected] (R.B.); [email protected] (S.K.); [email protected] (P.K.M.)
Satyajit Tripathy Department of Pharmacology, School of Medicine, Faculty of Health Sciences, University of the Free State, Bloemfontein 9300, South Africa; [email protected]
Motlalepula Matsabisa Department of Pharmacology, School of Medicine, Faculty of Health Sciences, University of the Free State, Bloemfontein 9300, South Africa; [email protected]
Pulok Mukherjee Department of Pharmaceutical Technology, School of Natural Product Studies, Jadavpur University, Kolkata 700032, India; [email protected] (B.D.); [email protected] (R.B.); [email protected] (S.K.); [email protected] (P.K.M.)

Keywords:

PHELA®, South African traditional preparation, RP-HPLC, herb-drug interaction, antibacterial, biofilm

Abstract

A South African traditional formulation, PHELA®, is consumed by the traditional people for severe chest problems with coughing, diarrhea, oral ulcers etc. The present study focused on establishing the anti-infective properties of a safe and standardized poly-herbal formulation through a series of criteria and specifications. Keywords: PHELA®, South African traditional preparation, RP-HPLC, herb-drug interaction, antibacterial, biofilm

Author Biography

Pulok Mukherjee, Department of Pharmaceutical Technology, School of Natural Product Studies, Jadavpur University, Kolkata 700032, India; [email protected] (B.D.); [email protected] (R.B.); [email protected] (S.K.); [email protected] (P.K.M.)

Institute of Bioresources and Sustainable Development, Department of Biotechnology, Government of India, Imphal 795001, India; [email protected]

Quality Related Safety Evaluation of a South African Traditional Formulation (PHELA®) as Novel Anti-Biofilm Candidate

Authors

Keywords:

Abstract

Author Biography

Pulok Mukherjee, Department of Pharmaceutical Technology, School of Natural Product Studies, Jadavpur University, Kolkata 700032, India; [email protected] (B.D.); [email protected] (R.B.); [email protected] (S.K.); [email protected] (P.K.M.)

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