Preprint / Version 1

GC–MS profiling and antibacterial activity of Solanum khasianum leaf and root extracts

Authors

  • Pavani Chirumamilla Department of Biotechnology, Kakatiya University, Warangal, Telangana 506009 India
  • Sunitha Dharavath Department of Biotechnology, Kakatiya University, Warangal, Telangana 506009 India
  • Shasthree Taduri Department of Biotechnology, Kakatiya University, Warangal, Telangana 506009 India

Keywords:

Solanum khasianum, GC–MS analysis, Antibacterial activity, Phytochemicals, Biological activity

Abstract

Solanum khasianum is an important medicinal herb of the Solanaceae family. The present study was focused to determine the bioactive compounds in S. khasianum leaf and root extract by GC–MS analysis and their antibacterial activity by agar well diffusion method. Results Sixteen bioactive compounds were detected in leaf extract and thirty-two compounds in root methanolic extract by GC–MS. The major potent compounds identified in leaf and root extracts were heptadecane 9-hexyl (43.65%) and stigmasterol (23.18%). The root extract showed increased antibacterial activity than leaf extract. Conclusion These extracts possessed significant antibacterial activity against the tested bacterial isolates in dose-dependent manner. This study provides the phytoconstituents, antibacterial property and scientific evidence for the traditional claim and use of S. khasianum. Keywords: Solanum khasianum, GC–MS analysis, Antibacterial activity, Phytochemicals, Biological activity

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