Preprint / Version 1

Exploration of Lamiaceae in Cardio Vascular Diseases and Functional Foods: Medicine as Food and Food as Medicine

Authors

  • Ishani Chakrabartty Department of Applied Biology, School of Biological Sciences, University of Science and Technology Meghalaya (USTM), Meghalaya, India
  • Yugal Mohanta Department of Applied Biology, School of Biological Sciences, University of Science and Technology Meghalaya (USTM), Meghalaya, India
  • Amilia Nongbet Department of Botany, School of Biological Sciences, University of Science and Technology Meghalaya (USTM), Meghalaya, India
  • Tapan Mohanta Natural and Medical Sciences Research Centre, University of Nizwa, Nizwa, Oman
  • Saurov Mahanta National Institute of Electronics and Information Technology (NIELIT), Guwahati Centre, Guwahati, India
  • Nibedita Das Department of Botany, School of Biological Sciences, University of Science and Technology Meghalaya (USTM), Meghalaya, India
  • Muthupandian Saravanan AMR and Nanotherapeutics Laboratory, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, India
  • Nanaocha Sharma Institute of Bioresources and Sustainable Development, Imphal, India

Keywords:

Lamiaceae, ethnopharmacology, CVD, functional food, medicine

Abstract

In the current scenario, cardiovascular disease (CVD) is one of the most life-threatening diseases that has caused high mortality worldwide. Several scientists, researchers, and doctors are now resorting to medicinal plants and their metabolites for the treatment of different diseases, including CVD. The present review focuses on one such family of medicinal plants, called Lamiaceae, which has relieving and preventive action on CVD. Lamiaceae has a cosmopolitan distribution and has great importance in the traditional system of medicine. Lamiaceae members exhibit a wide range of activities like antioxidant, antihyperlipidemic, vasorelaxant, and thrombolytic effect, both in vitro and in vivo–these are mechanisms that contribute to different aspects of CVD including stroke, heart attack, and others. These plants harbour an array of bioactive compounds like phenolic acids, flavonoids, alkaloids, and other phytochemicals responsible for these actions. The review also highlights that these plants are a rich source of essential nutrients and minerals like omega-3 and hence, can serve as essential sources of functional foods—this can have an additional role in the prevention of CVDs. However, limitations still exist, and extensive research needs to be conducted on the Lamiaceae family in the quest to develop new and effective plant-based drugs and functional foods that can be used to treat and prevent cardiovascular diseases worldwide. Keywords: Lamiaceae, ethnopharmacology, CVD, functional food, medicine

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