Mechanistic insights on burdock (Arctium lappa L.) extract effects on diabetes mellitus
Authors
Shakti Mondal
Department of Integrative Food, Bioscience and Biotechnology, Graduate School of Chonnam, National University, Gwangju, 61186 South Korea
Jong-Bang Eun
Department of Integrative Food, Bioscience and Biotechnology, Graduate School of Chonnam, National University, Gwangju, 61186 South Korea
Diabetes mellitus (DM) type 2 is amongst the most common chronic diseases, being responsible for various problems in humans and contributing to increased mortality rates worldwide. Fructooligosaccharide, which can be produced from the roots of burdock (Arctium lappa L.), has been shown to have a wide range of pharmacological proprieties, including antiviral, anti-inflammatory, hypolipidemic, and antidiabetic effects. Moreover, burdock also contains chlorogenic acid, which has been used in traditional medicine as an antioxidant. Considering its natural origin and minimal toxicity, burdock fructooligosaccharides (BFO) has gained considerable attention from researchers owing its wide, efficient, and beneficial action against DM. Although the effectiveness of fructooligosaccharide and chlorogenic acid has been extensively discussed, limited information is available on the application of burdock for DM treatment. In this review, we discuss the beneficial contributions, and the recent in vitro and in vivo analytical findings on A. lappa extract as DM therapy.
Keywords: Burdock, Diabetes mellitus, Chlorogenic acid, Fructooligosacchaeride
Author Biographies
Shakti Mondal, Department of Integrative Food, Bioscience and Biotechnology, Graduate School of Chonnam, National University, Gwangju, 61186 South Korea
Department of Food Processing and Preservation, Hajee Mohammad Danesh Science and Technology University, Dinajpur, 5200 Bangladesh
Jong-Bang Eun, Department of Integrative Food, Bioscience and Biotechnology, Graduate School of Chonnam, National University, Gwangju, 61186 South Korea
Department of Food Science and Technology, College of Agriculture and Life Sciences, Chonnam National University, Rm#110, CALS Bldg 3, Gwangju, 61186 South Korea
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