Preprint / Version 1

Biopharmaceutical potentials of Prosopis spp. (Mimosaceae, Leguminosa)

Authors

  • Santhaseelan Henciya aDepartment of Marine Science, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India
  • Prabha Seturaman cDepartment of Microbiology, Annai College of Arts & Science, Kumbakonam, Tamil Nadu, India
  • Arthur James aDepartment of Marine Science, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India
  • Yi-Hong Tsai dGraduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan
  • Rahul Nikam dGraduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan
  • Yang-Chang Wu dGraduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan
  • Hans-Uwe Dahms bDepartment of Biomedical Science and Environment Biology, College of Life Science, Kaohsiung Medical University, Kaohsiung, Taiwan
  • Fang Chang dGraduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan

Keywords:

medicinal application, natural product, Prosopis, secondary metabolite

Abstract

Prosopis is a commercially important plant genus, which has been used since ancient times, particularly for medicinal purposes. Traditionally, Paste, gum, and smoke from leaves and pods are applied for anticancer, antidiabetic, anti-inflammatory, and antimicrobial purposes. Components of Prosopis such as flavonoids, tannins, alkaloids, quinones, or phenolic compounds demonstrate potentials in various biofunctions, such as analgesic, anthelmintic, antibiotic, antiemetic, microbial antioxidant, antimalarial, anti-protozoal, antipustule, and antiulcer activities; enhancement of H+, K+, ATPases; oral disinfection; and probiotic and nutritional effects; as well as in other biopharmaceutical applications, such as binding abilities for tablet production. The compound juliflorine provides a cure in Alzheimer disease by inhibiting acetylcholine esterase at cholinergic brain synapses. Some indirect medicinal applications of Prosopis spp. are indicated, including antimosquito larvicidal activity, chemical synthesis by associated fungal or bacterial symbionts, cyanobacterial degradation products, “mesquite” honey and pollens with high antioxidant activity, etc. This review will reveal the origins, distribution, folk Keywords: medicinal application, natural product, Prosopis, secondary metabolite

Author Biographies

Santhaseelan Henciya, aDepartment of Marine Science, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India

bDepartment of Biomedical Science and Environment Biology, College of Life Science, Kaohsiung Medical University, Kaohsiung, Taiwan

Yang-Chang Wu, dGraduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan

hCenter for Molecular Medicine, China Medical University Hospital, Taichung, Taiwan

Hans-Uwe Dahms, bDepartment of Biomedical Science and Environment Biology, College of Life Science, Kaohsiung Medical University, Kaohsiung, Taiwan

iDepartment of Marine Biotechnology and Resources, National Sun Yat-sen University, Taiwan

Fang Chang, dGraduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan

lResearch Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

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