Preprint / Version 1

An Ayurvedic Medication (Chyawanprash) as a Prophylaxis for Non-Communicable Disease and Communicable Disease: A Protocol for Systematic Review and Meta-Analysis

Authors

  • Shubham Sharma Public Health, Indian Institute of Public Health Gandhinagar, Gandhinagar, IND
  • Khushboo Kumari Public Health, Indian Council of Medical Research, Rajendra Memorial Research Institute of Medical Sciences, Patna, IND
  • Gayathree Sethuraman Public Health, Triyog Ayurveda Hospital, Chennai, IND
  • Maya Abdelwahab Faculty of Medicine, Helwan University, Cairo, EGY
  • Suhasini Yadav Public Health, Collectives for Integrated Livelihood Initiatives "MADHUBAN", Mumbai, IND
  • Vangala Nandini Pharmacy, Annamacharya College of Pharmacy, Rajampeta, IND

Keywords:

srma, protocol, communicable disease, non communicable disease, chyawanprash

Abstract

Globally, non-communicable diseases (NCDs) and communicable diseases (CDs) are on the rise, posing a significant public health threat. A holistic ayurvedic preparation called chyawanprash (CP) has shown positive outcomes in NCDs and CDs. Hence, we aimed to report the outcomes in a systematic manner. To determine the safety, efficacy, healthcare utilization, and quality of life of CP as an optional therapy for NCD and CD management. This systematic review will adhere to PRISMA-P and Cochrane guidelines for methodological considerations. It will evaluate CP efficacy in diverse populations, considering Ayurvedic and non-Ayurvedic comparators. The study design will encompass randomized controlled trials (RCTs) published from 2010 to 2023 in healthcare settings, controlled environments, and communities. We will also analyze primary outcomes related to immunity biomarkers, vital signs, and secondary outcomes such as quality of life. Data sources and search strategy will involve systematic searches in databases such as Cochrane, PubMed, Google Scholar, Web of Science, and Scopus using MeSH terms and Boolean operators. Screening and data extraction will follow a standardized form with four independent reviewers. Quality assessment will use the Cochrane risk of bias tool. The systematic review will provide an exhaustive summary of the effectiveness and safety of CP to address the growing burden of NCDs and CDs. Registration: CRD42023418994. Keywords: srma, protocol, communicable disease, non communicable disease, chyawanprash

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