Preprint / Version 1

A Comprehensive Study of Therapeutic Applications of Chamomile

Authors

  • Amit Sah Department of Pharmaceutics, Delhi Institute of Pharmaceutical Sciences and Research, Delhi Pharmaceutical Sciences and Research University, Sector-3, M.B. Road, Pushp Vihar, New Delhi 110017, India
  • Punnoth Naseef Department of Pharmaceutics, Moulana College of Pharmacy, Perinthalmanna 679321, India
  • Mohammed Kuruniyan Department of Dental Technology, College of Applied Medical Sciences, King Khalid University, Abha 61421, Saudi Arabia
  • Gaurav Jain Department of Pharmaceutics, Delhi Institute of Pharmaceutical Sciences and Research, Delhi Pharmaceutical Sciences and Research University, Sector-3, M.B. Road, Pushp Vihar, New Delhi 110017, India
  • Foziyah Zakir Department of B. Pharm (Ayurveda), School of Pharmaceutical Sciences, Delhi Pharmaceutical Sciences and Research University, Sector-3, M.B. Road, Pushp Vihar, New Delhi 110017, India
  • Geeta Aggarwal Center for Advanced Formulation Development, Delhi Pharmaceutical Sciences and Research University, Sector-3, M.B. Road, Pushp Vihar, New Delhi 110017, India

Keywords:

apigenin, bisabalool, chamomile, chamomilla, flavonoid, matricaria

Abstract

Chamomile has a long history of traditional medicinal uses. The two commonly used varieties with therapeutic applications are German chamomile known as Matricaria chamomilla L. and Roman chamomile or Chamaemelum nobile L. The plant contains many components, namely, flavonoids, terpenoids, and coumarins, which are responsible for its medicinal properties. The review discusses recent developments that help in establishing its role as a therapeutic agent in various areas as an anti-inflammatory, antioxidant, analgesic, antimicrobial, hepatoprotective, anti-allergic, anticancer, and anti-hypertensive agent. Not much is known about its role in the treatment of CNS disorders and metabolic syndromes, which are also discussed. The chemical components responsible for the therapeutic activity and the respective mechanism of action are also elaborated. Keywords: apigenin, bisabalool, chamomile, chamomilla, flavonoid, matricaria

Author Biographies

Gaurav Jain, Department of Pharmaceutics, Delhi Institute of Pharmaceutical Sciences and Research, Delhi Pharmaceutical Sciences and Research University, Sector-3, M.B. Road, Pushp Vihar, New Delhi 110017, India

Center for Advanced Formulation Development, Delhi Pharmaceutical Sciences and Research University, Sector-3, M.B. Road, Pushp Vihar, New Delhi 110017, India

Geeta Aggarwal, Center for Advanced Formulation Development, Delhi Pharmaceutical Sciences and Research University, Sector-3, M.B. Road, Pushp Vihar, New Delhi 110017, India

Department of Pharmaceutics, School of Pharmaceutical Sciences, Delhi Pharmaceutical Sciences and Research University, Sector-3, M.B. Road, Pushp Vihar, New Delhi 110017, India

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