Preprint / Version 1

An insight into the potent medicinal plant Phyllanthus amarus Schum. and Thonn.

Authors

  • Aparupa Ghosh Plant Biology Lab, Organic & Medicinal Chemistry Division, CSIR-Indian Institute of Chemical Biology, 4, Raja S.C. Mullick Road, Kolkata, 700032 India
  • Anindita Banerjee Undergraduate, Postgraduate, and Research Department of Microbiology, St. Xavier’s College (Autonomous), 30 Mother Teresa Sarani, Kolkata, 700016 India
  • Sharmila Chattopadhyay Plant Biology Lab, Organic & Medicinal Chemistry Division, CSIR-Indian Institute of Chemical Biology, 4, Raja S.C. Mullick Road, Kolkata, 700032 India

Keywords:

Bioactivity, Genomics, Hepatoprotective, P. amarus, Secondary metabolites, Therapeutic efficacy

Abstract

Phyllanthus amarus Schum. and Thonn., a globally distributed herb is known for its several therapeutic potentials. P. amarus has a long history of use in the traditional system of medicine for over 2000 years owing to its wide array of secondary metabolites that confer significant medicinal attributes. Research on various aspects including ethnobotany, phytochemistry to bioactivity, or pharmacological studies has been conducted over the past several decades on this potent herb. P. amarus extracts have shown a broad range of pharmacological activities like hepatoprotective, antioxidant, antiviral, antimicrobial, antidiabetic, anti-inflammatory, anticancer, antimalarial, nephroprotective, diuretic, and several other properties. The present review compiles and covers literature and research of several groups across past decades to date and focuses on how the therapeutic significance of this plant can be further explored for future research either as herbal formulations, alternative medicine, or in the pharmaceutical industry. Supplementary Information The online version contains supplementary material available at 10.1007/s13237-022-00409-z. Keywords: Bioactivity, Genomics, Hepatoprotective, P. amarus, Secondary metabolites, Therapeutic efficacy

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