Bakuchiol, a natural constituent and its pharmacological benefits
Authors
Nuder Nizam
Department of Public Health, American International University Bangladesh, Dhaka, 1229, Bangladesh
Sohel Mahmud
Department of Biochemistry and Molecular Biology, Tajgaon College, Dhaka, National University, Bangladesh, Gazipur, 1704, Bangladesh
S Ark
Department of Biochemistry and Molecular Biology, Tajgaon College, Dhaka, National University, Bangladesh, Gazipur, 1704, Bangladesh
Mohammad Kamruzzaman
Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, 1902, Bangladesh
Md Hasan
Department of Biochemistry and Molecular Biology, Tajgaon College, Dhaka, National University, Bangladesh, Gazipur, 1704, Bangladesh
Amit Sharangi
Department of Plantation Spices Medicinal and Aromatic Crops, Bidhan Chandra Krishi Viswa Vidyalaya, Nadia, West Bengal, India
Naoufal Hachlafi
Universite Sidi Mohamed Ben Abdallah, Fes, Fes-Boulemane, Morocco
Amit Sharangi
Department of Plantation Spices Medicinal and Aromatic Crops, Bidhan Chandra Krishi Viswa Vidyalaya, Nadia, West Bengal, India
Md Hasan
North South University, Bangladesh
Keywords:
Bakuchiol, Psoralea corylifolia, medicinal plants, health benefits
Abstract
Background and aims
Natural compounds extracted from medicinal plants have recently gained attention in therapeutics as they are considered to have lower Toxicity and higher tolerability relative to chemically synthesized compounds. Bakuchiol from Psoralea corylifolia L. is one such compound; it is a type of meroterpene derived from the leaves and seeds of Psoralea corylifolia plants. Natural sources of bakuchiol have been used in traditional Chinese and Indian medicine for centuries due to its preventive benefits against tumors and inflammation. It plays a strong potential role as an antioxidant with impressive abilities to remove Reactive Oxygen Species (ROS). This review has focused on bakuchiol’s extraction, therapeutic applications, and pharmacological benefits.
Methods
A search strategy has been followed to retrieve the relevant newly published literature on the pharmacological benefits of bakuchiol. After an extensive study of the retrieved articles and maintaining the inclusion and exclusion criteria, 110 articles were finally selected for this review.
Results
Strong support of primary research on the protective effects via antitumorigenic, anti-inflammatory, antioxidative, antimicrobial, and antiviral activities are delineated.
Conclusions
From ancient to modern life, medicinal plants have always been drawing the attention of human beings to alleviate ailments for a healthy and balanced lifestyle. This review is a comprehensive approach to highlighting bona fide essential pharmacological benefits and mechanisms underlying their therapeutic applications.
Keywords: Bakuchiol, Psoralea corylifolia, medicinal plants, health benefits
Author Biographies
Nuder Nizam, Department of Public Health, American International University Bangladesh, Dhaka, 1229, Bangladesh
Data Curation, Investigation, Methodology, Visualization, Writing – Original Draft Preparation
Sohel Mahmud, Department of Biochemistry and Molecular Biology, Tajgaon College, Dhaka, National University, Bangladesh, Gazipur, 1704, Bangladesh
Data Curation, Visualization, Writing – Original Draft Preparation
S Ark, Department of Biochemistry and Molecular Biology, Tajgaon College, Dhaka, National University, Bangladesh, Gazipur, 1704, Bangladesh
Writing – Review & Editing
Mohammad Kamruzzaman, Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, 1902, Bangladesh
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