Preprint / Version 1

The use of complementary and traditional medicine for the treatment of patients with COVID-19: A systematic review

Authors

  • Barbara Badanta aDepartment of Nursing, Faculty of Nursing, Physiotherapy, and Podiatry, University of Sevilla, C/Avenzoar, 6, Spain
  • Marta García bFaculty of Nursing, Physiotherapy and Podiatry, University of Sevilla, Spain
  • Ángela Jiménez bFaculty of Nursing, Physiotherapy and Podiatry, University of Sevilla, Spain
  • Giancarlo Lucchetti cDepartment of Medicine, School of Medicine, Federal University of Juiz de Fora, Juiz de Fora 36036-900, Brazil
  • Rocío Diego-Cordero aDepartment of Nursing, Faculty of Nursing, Physiotherapy, and Podiatry, University of Sevilla, C/Avenzoar, 6, Spain

Keywords:

Complementary therapies, Coronavirus, COVID-19, Nonpharmacological interventions, Traditional medicine

Abstract

Objective The aim of this study was to evaluate the use and effectiveness of non-pharmacological therapies as part of the treatment of COVID-19 and its complications, either combined or not with the usual treatment. Methods A systematic review was conducted between August and October 2021 using PubMed, Scopus, CINAHL and Web of Science databases. From a total of 204 articles identified, 33 were included in the final sample (15 clinical trials and 18 quasi-experimental studies). The methodological evaluation was carried out using STROBE and CONSORT guidelines. Results There is a growing literature on the use of CAM for COVID-19. Most studies have shown positive findings, particularly for the use of TCM, other herbal therapies and acupuncture. Nevertheless, most studies were carried out in Asia and relied on quasi-experimental designs. The current evidence is available for physical outcomes (mortality rate, pneumonia resolution and other symptoms, negative PCR test, and hospitalization and ICU admissions) and for mental health outcomes. Conclusion Despite a positive role of CAM on COVID-19 outcomes, the evidence is still mostly based on quasi-experimental studies. More robust clinical trials are needed in order to generate better evidence in this area. Keywords: Complementary therapies, Coronavirus, COVID-19, Nonpharmacological interventions, Traditional medicine