A review on hypo-cholesterolemic activity of Nigella sativa seeds and its extracts
Authors
Karmegam Maheswari
Department of Physiology, Sri Ramachandra Medical College and Research Institute (SRMC & RI), Porur, Chennai- 600116, India
K Dilara
Department of Physiology, Sri Ramachandra Medical College and Research Institute (SRMC & RI), Porur, Chennai- 600116, India
S Vadivel
Department of Physiology, Karpaga Vinayaga Institute of Medical Education and Research, Madhuranthagam, Chengalpet-603308, Tamil Nadu, India
Priscilla Johnson
Department of Physiology, Sri Ramachandra Medical College and Research Institute (SRMC & RI), Porur, Chennai- 600116, India
Selvaraj Jayaraman
Department of Biochemistry, Saveetha Dental College & Hospital, Saveetha Institute of Medical & Technical Sciences, Chennai 600077, India
Keywords:
Nigella sativa, black seed, hypo cholesterolemic activity
Abstract
Nigella sativa (N. sativa) (Family Ranunculaceae) is a popular therapeutic herb in many parts of the world. It is widely used in traditional medical systems such as Unani, Ayurveda and Siddha. Seeds and oil have a long history of folkloric use in many medicinal and culinary systems. The seeds of N. sativa have long been used to treat a variety of illnesses and disorders. Studies on N. sativa and its therapeutic potential have been investigated. This includes anti-diabetic, anticancer, immune-modulatory, analgesic, antimicrobial, anti-inflammatory, spasmolytic, bronchodilator, hepato-protective, renal protective, gastro-protective, antioxidant properties, and several others. Nigella sativa contains thymoquinone. This is a bioactive component of the essential oil with medicinal benefits. Therefore, it is of interest to report a comprehensive data on the therapeutic usefulness of N. sativa in hypo-cholesterolemic activity.
Keywords: Nigella sativa, black seed, hypo cholesterolemic activity
Author Biography
Karmegam Maheswari, Department of Physiology, Sri Ramachandra Medical College and Research Institute (SRMC & RI), Porur, Chennai- 600116, India
Department of Physiology, Karpaga Vinayaga Institute of Medical Education and Research, Madhuranthagam, Chengalpet-603308, Tamil Nadu, India
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