Biochemical analysis of methanolic extract from Evolvulus alsinoides
Authors
Karnam Nithya
Department Of Pharmacology, Vinayaka Missions University, Salem (Deemed to be university), Chinna Seeragapadi, Salem - 636308, Tamilnadu, India
Rajaram Siddaraman
Department of Pharmacology, VMKV Medical College, Chinna Seeragapadi, Salem - 636308, Tamil Nadu, India
PP Sheelajoice
Department Of Physiology, VMKV Medical College, Chinna Seeragapadi, Salem - 636 308, Tamil Nadu, India
Mani Rajarathinam
Department Of Pharmacology, GMKMC Medical College, Shavapet Salem 636002, Tamil Nadu, India
Vurimi Chandra
Department of Pharmacology, Narayana Medical College, Nellore - 524 003, AP, India
Evolvulus alsinoides is a medicinal plant in the Convolvulaceae family. Traditionally, it is used for different ailments in India and in several other countries. It has a variety of pharmacological qualities, including those that aid wound healing, hepato-protection, cardio-protection, anti-diabetic action, asthma, and epilepsy, memory and learning, and neuroprotection. The whole plant is utilized in Ayurvedic medicine to treat neurological disorders, including amnesia, and it is called the brain tonic by them. Therefore, the use of GC-MS in phytochemical research and chemotaxonomic investigations of medicinal plants containing physiologically active components is critical. Hence, the various secondary metabolites from the methanolic extract of E. alsinoides were analyzed using GC-MS technique. The methanolic extract of E. alsinoides yielded ten compounds. All ten compounds showed the highest number of hits. Those with the highest concentration were chosen to identify the qualitative compound. All compounds are non-toxic. Molecules with specific properties are capable of modulating a variety of proteins, including some enzymes. Thus, these molecules are potential hit-to-lead molecules in preclinical studies.
Keywords: Phytochemistry, Evolvulus alsinoides, convolvulaceae, GCMS
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