Preprint / Version 1

Collision of herbal medicine and nanotechnology: a bibliometric analysis of herbal nanoparticles from 2004 to 2023

Authors

  • Sinan Ai China-Japan Friendship Hospital, Beijing, China
  • Yake Li Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China
  • Huijuan Zheng Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China
  • Meiling Zhang Beijing Friendship Hospital, Capital Medical University, Beijing, China
  • Jiayin Tao Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China
  • Weijing Liu Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China
  • Liang Peng China-Japan Friendship Hospital, Beijing, China
  • Zhen Wang Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China
  • Yaoxian Wang Henan University of Chinese Medicine, Zhengzhou, Henan China

Keywords:

Herbal nanoparticles, Herbal medicine, Traditional Chinese medicine, Nanoparticles, Bibliometric analysis, VOSviewer, Citespace

Abstract

Herbal nanoparticles are made from natural herbs/medicinal plants, their extracts, or a combination with other nanoparticle carriers. Compared to traditional herbs, herbal nanoparticles lead to improved bioavailability, enhanced stability, and reduced toxicity. Previous research indicates that herbal medicine nanomaterials are rapidly advancing and making significant progress; however, bibliometric analysis and knowledge mapping for herbal nanoparticles are currently lacking. We performed a bibliometric analysis by retrieving publications related to herbal nanoparticles from the Web of Science Core Collection (WoSCC) database spanning from 2004 to 2023. Data processing was performed using the R package Bibliometrix, VOSviewers, and CiteSpace. Results In total, 1876 articles related to herbal nanoparticles were identified, originating from various countries, with China being the primary contributing country. The number of publications in this field increases annually. Beijing University of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, and Saveetha University in India are prominent research institutions in this domain. The Journal “International Journal of Nanomedicine” has the highest number of publications. The number of authors of these publications reached 8234, with Yan Zhao, Yue Zhang, and Huihua Qu being the most prolific authors and Yan Zhao being the most frequently cited author. “Traditional Chinese medicine,” “drug delivery,” and “green synthesis” are the main research focal points. Themes such as “green synthesis,” “curcumin,” “wound healing,” “drug delivery,” and “carbon dots” may represent emerging research areas. Conclusions Our study findings assist in identifying the latest research frontiers and hot topics, providing valuable references for scholars investigating the role of nanotechnology in herbal medicine. Graphical Abstract Supplementary Information The online version contains supplementary material available at 10.1186/s12951-024-02426-3. Keywords: Herbal nanoparticles, Herbal medicine, Traditional Chinese medicine, Nanoparticles, Bibliometric analysis, VOSviewer, Citespace

Author Biographies

Sinan Ai, China-Japan Friendship Hospital, Beijing, China

Beijing Key Laboratory for Immune-Mediated Inflammatory Diseases, Institute of Medical Science, China-Japan Friendship Hospital, Beijing, China

Liang Peng, China-Japan Friendship Hospital, Beijing, China

Beijing Key Laboratory for Immune-Mediated Inflammatory Diseases, Institute of Medical Science, China-Japan Friendship Hospital, Beijing, China

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