Preprint / Version 1

Potential therapeutic effects of green tea (Camellia sinensis) in eye diseases, a review

Authors

  • Mohadese Boroughani aStudent research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
  • Zahra Tahmasbi aStudent research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
  • Mohamad Heidari aStudent research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
  • Mohammadkarim Johari bPoostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
  • Mohammad Hashempur cResearch Center for Traditional Medicine and History of Medicine, Department of Persian Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
  • Mojtaba Heydari bPoostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

Keywords:

Eye diseases, Ocular diseases, Green tea, Camellia sinensis, Catechin, Traditional Persian medicine, Integrative medicine

Abstract

This review aims to evaluate the therapeutic potential of green tea (GT), scientifically named Camellia sinensis, in treating eye diseases. We provide an overview of the ingredients and traditional use of Camellia sinensis, followed by a detailed discussion of its therapeutic uses in various eye diseases, including ocular surface diseases (allergic diseases, dry eye, pterygium, and infections), cataract, glaucoma, uveitis, retinal diseases, and optic nerve diseases. The pharmacologic activities related to ocular diseases, such as anti-vascular endothelial growth factor, aldose reductase inhibitor activity, anti-bacterial, anti-inflammatory, and antioxidant effects are also explored in this review. The dose and route of administration of GT in various studies are discussed. Safety issues related to the use of GT, such as the side effects associated with high doses and long-term use, are also addressed. The review highlights the potential of GT as a natural therapeutic agent for a variety of ocular diseases. Its various pharmacologic activities make it a promising treatment option. However, more well-designed studies are needed to determine the optimal dose and route of administration and to assess its long-term safety and efficacy. Overall, GT appears to be a promising adjunct therapy for various ocular diseases. Keywords: Eye diseases, Ocular diseases, Green tea, Camellia sinensis, Catechin, Traditional Persian medicine, Integrative medicine

Author Biography

Mojtaba Heydari, bPoostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

cResearch Center for Traditional Medicine and History of Medicine, Department of Persian Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

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