Antimicrobial efficacy of two commercially available herbal products with and without ultrasonic activation in primary endodontic infections: A randomized clinical trial
Authors
Drishti Palwankar
Department of Conservative Dentistry and Endodontics, Faculty of Dental Sciences, SGT University, Gurugram, Haryana, India
Ashima Garg
Department of Conservative Dentistry and Endodontics, Sudha Rustagi College of Dental Sciences and Research, SDS, MRIIRS, Faridabad, Haryana, India
Monika Tandan
Department of Conservative Dentistry and Endodontics, Manav Rachna Dental College, SDS, MRIIRS, Faridabad, Haryana, India
Prashant Bhasin
Department of Conservative Dentistry and Endodontics, Sudha Rustagi College of Dental Sciences and Research, Faridabad, Haryana, India
Akshat Sachdeva
Department of Conservative Dentistry and Endodontics, CDER, AIIMS, New Delhi, India
Pooja Palwankar
Department of Periodontology, Manav Rachna Dental College, SDS, MRIIRS, India
Effective irrigation is crucial for successful endodontic treatment. Traditional irrigants like sodium hypochlorite (NaOCl) have been widely used, but there is a growing interest in exploring natural alternatives for their potential antimicrobial properties.
Objective:
The study aims to compare the antimicrobial efficacy of Neem, Bitter Gourd, and NaOCl, with and without ultrasonic activation in managing primary endodontic infections.
Materials and Methods:
Ninety patients were randomly assigned six groups (n = 15) Group 1: NaOCl, Group 2: NaOCl with passive ultrasonic irrigation (PUI), Group 3: Neem juice, Group 4: Neem juice with PUI, Group 5: Bitter gourd juice, and Group 6: Bitter gourd juice with PUI. Bacteriological samples were collected before (S1) and after (S2) shaping, plated on brain heart infusion agar, and colony counting was done after 24 h.
Statistical Analysis Used:
Shapiro–Wilk test, one-way ANOVA, post hoc Tukey analysis, and paired t-test.
Results:
All the groups demonstrated a significant reduction in bacterial count. Groups with PUI (2, 4, 6) demonstrated higher mean bacterial reduction than their counterparts without PUI (1, 3, 5).
Conclusion:
Neem and Bitter gourd juices, particularly when used with PUI, demonstrated antimicrobial efficacy comparable to NaOCl with PUI.
Keywords: Antibacterial activity, bitter gourd juice, Neem juice, passive ultrasonic irrigation, sodium hypochlorite
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