Preprint / Version 1

Therapeutic potential of Lawsonia inermis Linn: a comprehensive overview

Authors

  • Gaber Batiha Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, 22511 AlBeheira Egypt
  • John Teibo Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
  • Hazem Shaheen Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, 22511 AlBeheira Egypt
  • Benjamin Babalola Biochemistry Division, Department of Chemistry, Purdue University, West Lafayette, IN 47907 USA
  • Titilade Teibo Department of Maternal-Infant and Public Health Nursing, College of Nursing, University of São Paulo, Ribeirão Preto, São Paulo Brazil
  • Hayder Al-kuraishy Department of Clinical Pharmacology and Therapeutic Medicine, College of Medicine, Almustansiriyiah University, Bagh-Dad, Iraq
  • Ali Al-Garbeeb Department of Clinical Pharmacology and Therapeutic Medicine, College of Medicine, Almustansiriyiah University, Bagh-Dad, Iraq
  • Athanasios Alexiou Department of Science and Engineering, Novel Global Community Educational Foundation, Hebersham, NSW 2770 Australia
  • Marios Papadakis Department of Surgery II, University Hospital Witten-Herdecke, University of Witten-Herdecke, Heusnerstrasse 40, 42283 Wuppertal, Germany

Keywords:

Lawsonia inermis, Pharmacological activities, Bioactive components, Drug development, Therapeutic benefits, Pharmacokinetics, Pharmacological side effects

Abstract

Lawsonia inermis Linn, commonly known as henna, is a member of the Lythraceae family and has been found to contain a variety of compounds with both industrial and medicinal applications in its stem, bark, roots, flowers, and seeds. This report provides a comprehensive review of the bioactive components, pharmacological activities, pharmacokinetics, and pharmacological side effects of Lawsonia inermis. Relevant materials were gathered from Google Scholar, PubMed, Scopus, and Web of Science and reviewed for important properties and updates about the plant. Lawsonia inermis contains a variety of bioactive compounds, including flavonoids, coumarins, triterpenoids, steroids, xanthones, polyphenols, fatty acids, alkaloids, quinones, tannins, leucocyandin, epicatechin, catechin, and quercetin. The plant is been traditionally used to treat numerous conditions, including ulcers, bronchitis, lumbago, hemicrania, leukoderma, scabies, boils, ophthalmic disorders, hair loss, and jaundice. It has also been found to possess a range of pharmacological activities, including antioxidant, anti-inflammatory, analgesic, antiparasitic, hepatoprotective, antifungal, antitumor, wound healing, and hypoglycemic effects. The potential of Lawsonia inermis for various biological applications is promising, and further studies are needed to fully explore its therapeutic benefits for various diseases of public health. Concern advances in drug development could enable the characterization of various bioactive constituents and facilitate their development and application for the benefit of humanity. Keywords: Lawsonia inermis, Pharmacological activities, Bioactive components, Drug development, Therapeutic benefits, Pharmacokinetics, Pharmacological side effects

Author Biography

Athanasios Alexiou, Department of Science and Engineering, Novel Global Community Educational Foundation, Hebersham, NSW 2770 Australia

AFNP Med, 1030 Vienna, Austria