Case Report: A Pathological Odyssey in Primary Cutaneous Apocrine Carcinoma
Authors
Dr Naseri
Department of Pathology, Jawaharlal Nehru Medical College, Datta Megha Institute of Higher Education and Research, Sawangi, Wardha, India
Rehan Zahid
Plastic Surgery, The University of Iowa Healthcare, Iowa City, IA, USA
Dr Naseri
Pathology, Jawaharlal Nehru Medical College, Datta Meghe Institue of Higher Education and Reaseach, Sawangi, Sawangi, Wardha, Maharashtra, India
Nour Kibbi
Stanford University School of Medicine, Palo Alto, California, USA
Rehan Zahid
Plastic Surgery, The University of Iowa Healthcare, Iowa City, IA, USA
Dr Barsagade
Andaman and Nicobar Islands Institute of Medical sciences, Port Blair, India
Sunita Vagha
Department of Pathology, Jawaharlal Nehru Medical College, Datta Megha Institute of Higher Education and Research, Sawangi, Wardha, India
Dr Acharya
Department of Medicine, Jawaharlal Nehru Medical College, Datta Megha Institute of Higher Education and Research, Sawangi, Wardha, India
Samarth Shukla
Department of Pathology, Jawaharlal Nehru Medical College, Datta Megha Institute of Higher Education and Research, Sawangi, Wardha, India
Dr Naseri
Pathology, Jawaharlal Nehru Medical College, Datta Meghe Institue of Higher Education and Reaseach, Sawangi, Sawangi, Wardha, Maharashtra, India
Apocrine carcinoma is an extremely rare malignant cutaneous neoplasm that usually arises in areas with a high density of apocrine glands. Diagnosis can be challenging as tumours share histological and immunophenotypic characteristics with them. At first evaluation, the disease is often assumed to be benign. There have been approximately 100 reports of apocrine neoplasms in the literature.
A 48-year-old male presented with a right axillary mass which increased in size over a period of 2 years. The patient was reported to have had ayurvedic therapy, but his swelling remained unchanged. Axillary lymph nodes were palpable. USG axilla suggested a well-defined fungating solid isoechoic lesion. USG neck did not reveal any abnormality. The mass was surgically excised as a whole by removing the overlying skin with margins and lymph node excision. The patient was diagnosed with primary apocrine carcinoma after surgical excision. The differentials include adenocarcinoma of breast and prostate and apocrine adenoma. There are no established standards for the care of this form of carcinoma due to its rarity and the absence of clinical studies. A literature evaluation and further reporting will aid in developing diagnostic standards and the most efficient treatment options.
Keywords: Apocrine carcinoma, Axillary mass, rare presentation, apocrine neoplasms, solid lesion, lymph node excision, malignant, surgical excision.
Author Biographies
Dr Naseri, Department of Pathology, Jawaharlal Nehru Medical College, Datta Megha Institute of Higher Education and Research, Sawangi, Wardha, India
Conceptualization, Data Curation, Formal Analysis, Investigation, Methodology, Resources, Writing – Original Draft Preparation, Writing – Review & Editing
Rehan Zahid, Plastic Surgery, The University of Iowa Healthcare, Iowa City, IA, USA
Referee
Nour Kibbi, Stanford University School of Medicine, Palo Alto, California, USA
Referee
Rehan Zahid, Plastic Surgery, The University of Iowa Healthcare, Iowa City, IA, USA
Referee
Dr Barsagade, Andaman and Nicobar Islands Institute of Medical sciences, Port Blair, India
Referee
Sunita Vagha, Department of Pathology, Jawaharlal Nehru Medical College, Datta Megha Institute of Higher Education and Research, Sawangi, Wardha, India
Supervision, Validation
Dr Acharya, Department of Medicine, Jawaharlal Nehru Medical College, Datta Megha Institute of Higher Education and Research, Sawangi, Wardha, India
Supervision
Samarth Shukla, Department of Pathology, Jawaharlal Nehru Medical College, Datta Megha Institute of Higher Education and Research, Sawangi, Wardha, India
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