Preprint / Version 1

Case Report: A Pathological Odyssey in Primary Cutaneous Apocrine Carcinoma

Authors

  • Dr Naseri Department of Pathology, Jawaharlal Nehru Medical College, Datta Megha Institute of Higher Education and Research, Sawangi, Wardha, India
  • Rehan Zahid Plastic Surgery, The University of Iowa Healthcare, Iowa City, IA, USA
  • Dr Naseri Pathology, Jawaharlal Nehru Medical College, Datta Meghe Institue of Higher Education and Reaseach, Sawangi, Sawangi, Wardha, Maharashtra, India
  • Nour Kibbi Stanford University School of Medicine, Palo Alto, California, USA
  • Rehan Zahid Plastic Surgery, The University of Iowa Healthcare, Iowa City, IA, USA
  • Dr Barsagade Andaman and Nicobar Islands Institute of Medical sciences, Port Blair, India
  • Sunita Vagha Department of Pathology, Jawaharlal Nehru Medical College, Datta Megha Institute of Higher Education and Research, Sawangi, Wardha, India
  • Dr Acharya Department of Medicine, Jawaharlal Nehru Medical College, Datta Megha Institute of Higher Education and Research, Sawangi, Wardha, India
  • Samarth Shukla Department of Pathology, Jawaharlal Nehru Medical College, Datta Megha Institute of Higher Education and Research, Sawangi, Wardha, India
  • Dr Naseri Pathology, Jawaharlal Nehru Medical College, Datta Meghe Institue of Higher Education and Reaseach, Sawangi, Sawangi, Wardha, Maharashtra, India

Keywords:

Apocrine carcinoma, Axillary mass, rare presentation, apocrine neoplasms, solid lesion, lymph node excision, malignant, surgical excision.

Abstract

Apocrine carcinoma is an extremely rare malignant cutaneous neoplasm that usually arises in areas with a high density of apocrine glands. Diagnosis can be challenging as tumours share histological and immunophenotypic characteristics with them. At first evaluation, the disease is often assumed to be benign. There have been approximately 100 reports of apocrine neoplasms in the literature. A 48-year-old male presented with a right axillary mass which increased in size over a period of 2 years. The patient was reported to have had ayurvedic therapy, but his swelling remained unchanged. Axillary lymph nodes were palpable. USG axilla suggested a well-defined fungating solid isoechoic lesion. USG neck did not reveal any abnormality. The mass was surgically excised as a whole by removing the overlying skin with margins and lymph node excision. The patient was diagnosed with primary apocrine carcinoma after surgical excision. The differentials include adenocarcinoma of breast and prostate and apocrine adenoma. There are no established standards for the care of this form of carcinoma due to its rarity and the absence of clinical studies. A literature evaluation and further reporting will aid in developing diagnostic standards and the most efficient treatment options. Keywords: Apocrine carcinoma, Axillary mass, rare presentation, apocrine neoplasms, solid lesion, lymph node excision, malignant, surgical excision.

Author Biographies

Dr Naseri, Department of Pathology, Jawaharlal Nehru Medical College, Datta Megha Institute of Higher Education and Research, Sawangi, Wardha, India

Conceptualization, Data Curation, Formal Analysis, Investigation, Methodology, Resources, Writing – Original Draft Preparation, Writing – Review & Editing

Rehan Zahid, Plastic Surgery, The University of Iowa Healthcare, Iowa City, IA, USA

Referee

Nour Kibbi, Stanford University School of Medicine, Palo Alto, California, USA

Referee

Rehan Zahid, Plastic Surgery, The University of Iowa Healthcare, Iowa City, IA, USA

Referee

Dr Barsagade, Andaman and Nicobar Islands Institute of Medical sciences, Port Blair, India

Referee

Sunita Vagha, Department of Pathology, Jawaharlal Nehru Medical College, Datta Megha Institute of Higher Education and Research, Sawangi, Wardha, India

Supervision, Validation

Dr Acharya, Department of Medicine, Jawaharlal Nehru Medical College, Datta Megha Institute of Higher Education and Research, Sawangi, Wardha, India

Supervision

Samarth Shukla, Department of Pathology, Jawaharlal Nehru Medical College, Datta Megha Institute of Higher Education and Research, Sawangi, Wardha, India

Conceptualization, Project Administration, Supervision, Validation, Visualization

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